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Luxi Xia

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Articles 13
Citations 193
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Recent Articles
1.
Donnelly W, Haynes R, Commons K, Erickson D, Panzini C, Xia L, et al.
Exp Neurol . 2019 Dec; 326:113166. PMID: 31887303
We tested the hypothesis that exposure to intermittent hypoxia (IH) during pregnancy would prolong the laryngeal chemoreflex (LCR) and diminish the capacity of serotonin (5-hydroxytryptamine; 5-HT) to terminate the LCR....
2.
Donnelly W, Xia L, Bartlett D, Leiter J
Exp Physiol . 2017 Jul; 102(8):1007-1018. PMID: 28675564
What is the central question of this study? Does activation of serotonergic neurons in the caudal medullary raphe, some of which project to the nucleus of the solitary tract, shorten...
3.
Xia L, Bartlett Jr D, Leiter J
Respir Physiol Neurobiol . 2016 May; 230:44-53. PMID: 27181326
Thermal stress and prior upper respiratory tract infection are risk factors for the Sudden Infant Death Syndrome. The adverse effects of prior infection are likely mediated by interleukin-1β (IL-1β). Therefore,...
4.
Xia L, Bartlett Jr D, Leiter J
Respir Physiol Neurobiol . 2011 Feb; 176(1-2):21-31. PMID: 21276877
Elevating body temperature or just the temperature of the dorsal medulla by approximately 2°C prolongs the laryngeal chemoreflex (LCR) in decerebrate neonatal piglets. We tested the hypothesis that transient receptor...
5.
Duy P, Xia L, Bartlett Jr D, Leiter J
Exp Physiol . 2010 Apr; 95(7):774-87. PMID: 20418346
Hyperthermic prolongation of the laryngeal chemoreflex (LCR) in decerebrate piglets is prevented or reversed by GABA(A) receptor antagonists and adenosine A(2A) (Ad-A(2A)) receptor antagonists administered in the nucleus of the...
6.
Xia L, Crane-Godreau M, Leiter J, Bartlett Jr D
Respir Physiol Neurobiol . 2008 Dec; 165(2-3):161-6. PMID: 19041957
Laryngeal chemoreflex (LCR) apnea occurs in infant mammals of many species in response to water or other liquids in the laryngeal lumen. The apnea can last for many seconds, sometimes...
7.
Xia L, Bartlett Jr D, Leiter J
Respir Physiol Neurobiol . 2008 Sep; 164(3):358-65. PMID: 18775519
Hyperthermia prolongs the laryngeal chemoreflex (LCR). Under normothermic conditions, adenosine antagonists shorten and adenosine A(2A) (Ad-A(2A)) agonists prolong the LCR. Therefore, we tested the hypothesis that SCH-58261, an Ad-A(2A) receptor...
8.
Xia L, Damon T, Leiter J, Bartlett Jr D
Adv Exp Med Biol . 2007 Dec; 605:249-54. PMID: 18085281
We investigated the interaction between body temperature and the duration of the laryngeal chemoreflex (LCR) in decerebrate piglets. Elevating body temperature by approximately 2 degrees C prolongs the duration of...
9.
Xia L, Leiter J, Bartlett Jr D
J Appl Physiol (1985) . 2007 Oct; 104(1):269-74. PMID: 17962578
In neonatal mammals of many species, including human infants, apnea and other reflex responses frequently arise from stimulation of laryngeal receptors by ingested or regurgitated liquids. These reflexes, mediated by...
10.
Xia L, Damon T, Niblock M, Bartlett Jr D, Leiter J
J Appl Physiol (1985) . 2007 Sep; 103(5):1864-72. PMID: 17823299
The laryngeal chemoreflex (LCR) is elicited by water in the larynx and leads to apnea and respiratory disruption in immature animals. The LCR is exaggerated by the elevation of brain...