Lumi Negishi
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Explore the profile of Lumi Negishi including associated specialties, affiliations and a list of published articles.
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49
Citations
808
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Recent Articles
11.
Shimizu K, Negishi L, Ito T, Touma S, Matsumoto T, Awaji M, et al.
Comp Biochem Physiol Part D Genomics Proteomics
. 2022 Sep;
44:101025.
PMID: 36075178
The molluscan shell is a good model for understanding the mechanisms underlying biomineralization. It is composed of calcium carbonate crystals and many types of organic molecules, such as the matrix...
12.
Shimizu K, Takeuchi T, Negishi L, Kurumizaka H, Kuriyama I, Endo K, et al.
Mol Biol Evol
. 2022 Jul;
39(7).
PMID: 35796746
Several types of shell matrix proteins (SMPs) have been identified in molluskan shells. Their diversity is the consequence of various molecular processes, including domain shuffling and gene duplication. However, the...
13.
Hatazawa S, Liu J, Takizawa Y, Zandian M, Negishi L, Kutateladze T, et al.
iScience
. 2022 Jun;
25(7):104563.
PMID: 35754730
p300 is a human acetyltransferase that associates with chromatin and mediates vital cellular processes. We now report the cryo-electron microscopy structures of the p300 catalytic core in complex with the...
14.
Itakura M, Yamaguchi K, Kitazawa R, Lim S, Anan Y, Yoshitake J, et al.
Nat Commun
. 2022 May;
13(1):2974.
PMID: 35624109
Reducing sugars can covalently react with proteins to generate a heterogeneous and complex group of compounds called advanced glycation end products (AGEs). AGEs are generally considered as pathogenic molecules, mediating...
15.
Yamada H, Nishida K, Iwasaki Y, Isota Y, Negishi L, Siomi M
Nat Commun
. 2022 Mar;
13(1):1518.
PMID: 35314687
Bombyx Papi acts as a scaffold for Siwi-piRISC biogenesis on the mitochondrial surface. Papi binds first to Siwi via the Tudor domain and subsequently to piRNA precursors loaded onto Siwi...
16.
Matsuura K, Kobayashi S, Konno K, Yamasaki M, Horiuchi T, Senda T, et al.
J Neurosci
. 2022 Feb;
42(12):2448-2473.
PMID: 35121636
Signal-induced proliferation-associated 1 (SIPA1)-like 1 (SIPA1L1; also known as SPAR1) has been proposed to regulate synaptic functions that are important in maintaining normal neuronal activities, such as regulating spine growth...
17.
Hirai S, Tomimatsu K, Miyawaki-Kuwakado A, Takizawa Y, Komatsu T, Tachibana T, et al.
Nucleic Acids Res
. 2021 Dec;
50(1):72-91.
PMID: 34929737
Histone H3mm18 is a non-allelic H3 variant expressed in skeletal muscle and brain in mice. However, its function has remained enigmatic. We found that H3mm18 is incorporated into chromatin in...
18.
Zheng Z, Kawakami K, Zhang D, Negishi L, Abomosallam M, Asakura T, et al.
Sci Rep
. 2021 May;
11(1):11306.
PMID: 34050239
The Pacific oyster, Crassostrea gigas, is a traditional food worldwide. The soft body of the oyster can easily accumulate heavy metals such as cadmium (Cd). To clarify the molecular mechanism...
19.
Murakami R, Sumiyoshi T, Negishi L, Siomi M
EMBO Rep
. 2021 Feb;
22(4):e51313.
PMID: 33555135
The piRNA amplification pathway in Bombyx is operated by Ago3 and Siwi in their piRISC form. The DEAD-box protein, Vasa, facilitates Ago3-piRISC production by liberating cleaved RNAs from Siwi-piRISC in...
20.
Piwi suppresses transcription of Brahma-dependent transposons via Maelstrom in ovarian somatic cells
Onishi R, Sato K, Murano K, Negishi L, Siomi H, Siomi M
Sci Adv
. 2020 Dec;
6(50).
PMID: 33310860
Piwi associates with PIWI-interacting RNAs (piRNAs) and represses transposons transcriptionally through heterochromatinization; however, this process is poorly understood. Here, we identify Brahma (Brm), the core adenosine triphosphatase of the SWI/SNF...