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Luke W Wenger

Explore the profile of Luke W Wenger including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 36
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Recent Articles
1.
Goering J, Wenger L, Stetsiv M, Moedritzer M, Hall E, Isai D, et al.
Hum Mol Genet . 2021 Jul; 31(1):18-31. PMID: 34302166
Patients with autosomal dominant SPECC1L variants show syndromic malformations, including hypertelorism, cleft palate and omphalocele. These SPECC1L variants largely cluster in the second coiled-coil domain (CCD2), which facilitates association with...
2.
Goering J, Isai D, Hall E, Wilson N, Kosa E, Wenger L, et al.
Sci Rep . 2021 Jan; 11(1):1452. PMID: 33446878
Cleft lip and/or palate (CL/P) are common anomalies occurring in 1/800 live-births. Pathogenic SPECC1L variants have been identified in patients with CL/P, which signifies a primary role for SPECC1L in...
3.
Hall E, Wenger L, Wilson N, Undurty-Akella S, Standley J, Augustine-Akpan E, et al.
Hum Mol Genet . 2020 Jan; 29(5):845-858. PMID: 31943082
SPECC1L mutations have been identified in patients with rare atypical orofacial clefts and with syndromic cleft lip and/or palate (CL/P). These mutations cluster in the second coiled-coil and calponin homology...
4.
Hodgson J, Wenger L, Clem R, Passarelli A
Sci Rep . 2019 Oct; 9(1):14494. PMID: 31601846
Prior studies have suggested that insect DNA viruses are negatively affected by dicer-2-mediated RNA interference (RNAi). To examine this further, we utilized an in vitro assay to measure dicer activity...
5.
Merkes C, Turkalo T, Wilder N, Park H, Wenger L, Lewin S, et al.
PLoS One . 2015 Jan; 10(1):e0116627. PMID: 25617839
Ewing sarcoma is the second most common skeletal (bone and cartilage) cancer in adolescents, and it is characterized by the expression of the aberrant chimeric fusion gene EWS/FLI1. Wild-type EWS...