Luke A Allen
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Explore the profile of Luke A Allen including associated specialties, affiliations and a list of published articles.
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13
Citations
205
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Recent Articles
1.
Roy B, Ogren J, Allen L, Diehl B, Sankar R, Lhatoo S, et al.
Pediatr Res
. 2024 Jul;
96(7):1732-1738.
PMID: 38992155
Background: Potential failing adult brain sites, stratified by risk, mediating Sudden Unexpected Death in Epilepsy (SUDEP) have been described, but are unknown in children. Methods: We examined regional brain volumes...
2.
Legouhy A, Allen L, Vos S, Oliveira J, Kassinopoulos M, Winston G, et al.
Epilepsy Res
. 2023 Apr;
192:107139.
PMID: 37068421
Although the mechanisms of sudden unexpected death in epilepsy (SUDEP) are not yet well understood, generalised- or focal-to-bilateral tonic-clonic seizures (TCS) are a major risk factor. Previous studies highlighted alterations...
3.
Legouhy A, Allen L, Vos S, Oliveira J, Kassinopoulos M, Winston G, et al.
medRxiv
. 2023 Mar;
PMID: 36993394
Although the mechanisms of sudden unexpected death in epilepsy (SUDEP) are not yet well understood, generalised- or focal-to-bilateral tonic-clonic seizures (TCS) are a major risk factor. Previous studies highlighted alterations...
4.
Sauder C, Allen L, Baker E, Miller A, Paul S, Brannan S
Transl Psychiatry
. 2022 Nov;
12(1):491.
PMID: 36414626
The muscarinic receptor agonist xanomeline improved cognition in phase 2 trials in Alzheimer's disease and schizophrenia. We present data on the effect of KarXT (xanomeline-trospium) on cognition in schizophrenia from...
5.
Ogren J, Allen L, Roy B, Diehl B, Stern J, Eliashiv D, et al.
PLoS One
. 2022 Sep;
17(9):e0274514.
PMID: 36137154
Patients with epilepsy, who later succumb to sudden unexpected death, show altered brain tissue volumes in selected regions. It is unclear whether the alterations in brain tissue volume represent changes...
6.
Whatley B, Winston J, Allen L, Vos S, Jha A, Scott C, et al.
Front Neurol
. 2021 Dec;
12:623358.
PMID: 34899550
To characterize regional brain metabolic differences in patients at high risk of sudden unexpected death in epilepsy (SUDEP), using fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET). We studied patients with refractory focal...
7.
Caciagli L, Allen L, He X, Trimmel K, Vos S, Centeno M, et al.
Neurology
. 2020 Aug;
95(17):e2427-e2441.
PMID: 32847951
Objective: To investigate the functional correlates of recurrent secondarily generalized seizures in temporal lobe epilepsy (TLE) using task-based fMRI as a framework to test for epilepsy-specific network rearrangements. Because the...
8.
Allen L, Harper R, Vos S, Scott C, Lacuey N, Vilella L, et al.
Epilepsia
. 2020 Jul;
61(8):1570-1580.
PMID: 32683693
Objectives: Hypoxia, or abnormally low blood-oxygen levels, often accompanies seizures and may elicit brain structural changes in people with epilepsy which contribute to central processes underlying sudden unexpected death in...
9.
Allen L, Harper R, Lhatoo S, Lemieux L, Diehl B
Front Neurol
. 2019 Mar;
10:185.
PMID: 30891003
The elusive nature of sudden unexpected death in epilepsy (SUDEP) has led to investigations of mechanisms and identification of biomarkers of this fatal scenario that constitutes the leading cause of...
10.
Allen L, Vos S, Kumar R, Ogren J, Harper R, Winston G, et al.
Epilepsia
. 2019 Mar;
60(4):718-729.
PMID: 30868560
Objective: The processes underlying sudden unexpected death in epilepsy (SUDEP) remain elusive, but centrally mediated cardiovascular or respiratory collapse is suspected. Volume changes in brain areas mediating recovery from extreme...