Lukasz P Gondek
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Explore the profile of Lukasz P Gondek including associated specialties, affiliations and a list of published articles.
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61
Citations
1222
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Recent Articles
1.
Hong Y, Pasca S, Shi W, Puiu D, Lake N, Lek M, et al.
Nat Commun
. 2024 Nov;
15(1):10133.
PMID: 39578475
Clonal hematopoiesis of indeterminate potential is the primary pathogenic risk factor for myeloid neoplasms, while heteroplasmy (mutations in a subset of cellular mitochondrial DNA) is another marker of clonal expansion...
2.
Hilgart E, Zhou W, Martinez-Montes E, Idrizi A, Tryggvadottir R, Gondek L, et al.
bioRxiv
. 2024 Nov;
PMID: 39554147
Disruption of the epigenetic landscape is of particular interest in acute myeloid leukemia (AML) due to its relatively low mutational burden and frequent occurrence of mutations in epigenetic regulators. Here,...
3.
Marshall C, Gondek L, Daniels V, Lu C, Pasca S, Xie J, et al.
Prostate
. 2024 Apr;
84(10):954-958.
PMID: 38641986
Background: Poly ADP-ribose polymerase (PARP) inhibitors are approved for the treatment of some men with advanced prostate cancer. Rare but serious side effects include myelodysplastic syndrome (MDS) and acute myeloid...
4.
Imus P, Pasca S, Tsai H, Aljawai Y, Cooke K, Walston J, et al.
Blood Adv
. 2024 Apr;
8(14):3849-3858.
PMID: 38640196
Allogeneic blood and marrow transplantation (alloBMT) is increasingly being used in older patients with blood cancer. Aging is associated with an increasing incidence of clonal hematopoiesis (CH). Although the effects...
5.
Gibson C, Lindsley R, Gondek L
Semin Hematol
. 2024 Mar;
61(1):9-15.
PMID: 38429201
Clonal hematopoiesis (CH) in autologous transplant recipients and allogeneic transplant donors has genetic features and clinical associations that are distinct from each other and from non-cancer populations. CH in the...
6.
Ravindra N, Dillon L, Gui G, Smith M, Gondek L, Jones R, et al.
Bone Marrow Transplant
. 2024 Jan;
59(3):428-430.
PMID: 38182672
No abstract available.
7.
Klausner M, Phan B, Morsberger L, Parish R, Shane A, Park R, et al.
Blood Cancer J
. 2023 Nov;
13(1):163.
PMID: 37926709
No abstract available.
8.
Hong Y, Battle S, Shi W, Puiu D, Pillalamarri V, Xie J, et al.
Nat Commun
. 2023 Sep;
14(1):6113.
PMID: 37777527
Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 ...
9.
Pasca S, Haldar S, Ambinder A, Webster J, Jain T, Dalton W, et al.
Haematologica
. 2023 Sep;
109(3):948-952.
PMID: 37731390
No abstract available.
10.
Ravindra N, Dillon L, Gui G, Smith M, Gondek L, Jones R, et al.
medRxiv
. 2023 Sep;
PMID: 37662423
The presence of measurable residual disease (MRD) prior to an allogeneic hematopoietic transplant (alloHCT) in Acute Myeloid Leukemia (AML) has been shown to be associated with an increased risk of...