Lujin Wu
Overview
Explore the profile of Lujin Wu including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
766
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0
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Recent Articles
11.
Wu L, Wang W, Dai M, Li H, Chen C, Wang D
BMC Cancer
. 2019 Dec;
19(1):1166.
PMID: 31791289
Background: Lung cancer (LC) is one of the leading causes of death worldwide, which highlights the urgent need for better therapies. Peroxisome proliferator-activated nuclear receptor alpha (PPARα), known as a...
12.
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, et al.
J Cell Physiol
. 2018 Nov;
234(7):11587-11601.
PMID: 30488495
Background: Cardiac hypertrophy and heart failure are characterized by increased late sodium current and abnormal Ca handling. Ranolazine, a selective inhibitor of the late sodium current, can reduce sodium accumulation...
13.
Dai M, Wu L, Tu L, Xu X, Wang D
Prostaglandins Other Lipid Mediat
. 2018 Oct;
139:36-40.
PMID: 30296488
Macrophages in adipose tissue are associated with obesity-induced low-grade inflammation, which contributed to insulin resistance and the related metabolic diseases. Macrophages display phenotypic plasticity, and polarize under the condition of...
14.
Wu L, Wang K, Wang W, Wen Z, Wang P, Liu L, et al.
Aging Cell
. 2018 Apr;
17(4):e12763.
PMID: 29659121
Lipotoxicity cardiomyopathy is the result of excessive accumulation and oxidation of toxic lipids in the heart. It is a major threat to patients with diabetes. Glucagon-like peptide-1 (GLP-1) has aroused...
15.
Yan H, Yi S, Zhuang H, Wu L, Wang D, Jiang J
Int J Mol Med
. 2017 Dec;
41(3):1704-1714.
PMID: 29286094
Inhibition of histone deacetylase-2 (HDAC2), which is a prohypertrophic factor in the heart, can functionally attenuate cardiac hypertrophy. The present study aimed to investigate whether sphingosine‑1‑phosphate (S1P), which has recently...
16.
Wang B, Nie J, Wu L, Hu Y, Wen Z, Dong L, et al.
Circ Res
. 2017 Dec;
122(5):712-729.
PMID: 29284690
Rationale: Mitochondrial dysfunction plays an important role in heart failure (HF). However, the molecular mechanisms regulating mitochondrial functions via selective mitochondrial autophagy (mitophagy) are poorly understood. Objective: We sought to...
17.
Wu L, Zhao F, Dai M, Li H, Chen C, Nie J, et al.
Hypertension
. 2017 Aug;
70(4):759-769.
PMID: 28827474
Inflammation plays a critical role in adverse cardiac remodeling and heart failure. The P2y12 receptor is one of the predominant activating receptors for platelets, thus initiating inflammatory responses under various...
18.
Dai M, Wu L, Wang P, Wen Z, Xu X, Wang D
Sci Rep
. 2017 Apr;
7:46743.
PMID: 28440284
Macrophages in adipose tissue are associated with obesity-induced low-grade inflammation, which contributed to insulin resistance and the related metabolic diseases. Previous studies demonstrated the beneficial effects of epoxyeicosatrienoic acids (EETs)...
19.
Dai M, Wu L, He Z, Zhang S, Chen C, Xu X, et al.
J Cell Physiol
. 2015 Jan;
230(9):2108-19.
PMID: 25626689
Macrophages, owning tremendous phenotypic plasticity and diverse functions, were becoming the target cells in various inflammatory, metabolic and immune diseases. Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to form...