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Luiza Helena Gremski

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Articles 40
Citations 465
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Recent Articles
1.
Wille A, Machado M, Souza S, Justa H, Fraga-Ferreira M, Mello E, et al.
Toxins (Basel) . 2025 Feb; 17(2). PMID: 39998087
Accidents caused by spiders, commonly known as brown spiders, are frequent in warm and temperate regions worldwide, with a higher prevalence in South America and the southern United States. In...
2.
Schluga P, Larangote D, de Melo A, Lobermayer G, Torrejon D, Souza de Oliveira L, et al.
Toxins (Basel) . 2024 Nov; 16(11). PMID: 39591241
Viperid snake venoms are notably abundant in metalloproteinases (proteins) (SVMPs), which are primarily responsible for inducing hemorrhage and disrupting the hemostatic process and tissue integrity in envenomed victims. In this...
3.
Justa H, Baldissera A, Machado M, Souza S, Polli N, Boia-Ferreira M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2024 Nov; 1870(2):159579. PMID: 39547302
Members of the phospholipase D (PLD) superfamily found in Loxosceles spider venoms are potent toxins with inflammatory and necrotizing activities. They degrade phospholipids in cell membranes, generating bioactive molecules that...
4.
Theodoro J, Justa H, Schluga P, Fischer M, Minozzo J, Gremski L, et al.
Int J Biol Macromol . 2024 Sep; 280(Pt 4):136108. PMID: 39343256
Spiders of Loxosceles genus, or Brown spiders produce a potent venom with minimal volume and protein content. Among its toxins, phospholipases D (PLDs) are notable for causing primary local and...
5.
Polli N, Ferreira M, Schluga P, Antunes B, Justa H, Theodoro J, et al.
Acta Trop . 2024 Aug; 258:107354. PMID: 39106916
Loxoscelism is the pathological condition triggered by a brown spider bite. The venom of these spiders is rich in phospholipases D (PLDs), which can induce virtually all local and systemic...
6.
Boia-Ferreira M, Moreno K, Basilio A, da Silva L, Vuitika L, Soley B, et al.
Cells . 2024 Jul; 13(13). PMID: 38995018
In the original publication [...].
7.
Justa H, Gonzalez J, Vuitika L, Mariutti R, Magnago P, de Moraes F, et al.
Int J Mol Sci . 2023 Aug; 24(15). PMID: 37569382
Spiders of genus are widely distributed and their venoms contain phospholipases D (PLDs), which degrade phospholipids and trigger inflammatory responses, dermonecrosis, hematological changes, and renal injuries. Biochemical, functional, and structural...
8.
Baldissera A, Boia-Ferreira M, Basilio A, Resende J, Castro M, Chaim O, et al.
Adv Med Sci . 2023 Jun; 68(2):227-237. PMID: 37379765
Purpose: This study aimed to evaluate the role of Translationally Controlled Tumor Protein (TCTP) in breast cancer (BC) and investigate the effects of sertraline, a serotonin selective reuptake inhibitor (SSRI),...
9.
Chaves-Moreira D, Gremski L, de Moraes F, Vuitika L, Wille A, Gonzalez J, et al.
Toxins (Basel) . 2023 Feb; 15(2). PMID: 36828423
Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade...
10.
Antunes B, Polli N, Schluga P, Silva T, Wille A, Locatelli-Dittrich R, et al.
Biomedicines . 2023 Jan; 11(1). PMID: 36672587
Loxoscelism is the clinical condition triggered after the bite of spiders of the genus . The main species involved in accidents in South America are , and . The only...