Luiz R G Bechara
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Explore the profile of Luiz R G Bechara including associated specialties, affiliations and a list of published articles.
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27
Citations
1670
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Recent Articles
1.
Elezaby A, Lin A, Vijayan V, Pokhrel S, Kraemer B, Bechara L, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(8):987-1002.
PMID: 39196031
Cardiac troponin I (cTnI) is a key regulator of cardiomyocyte contraction. However, its role in mitochondria is unknown. Here we show that cTnI localized to mitochondria in the heart, inhibited...
2.
Ferreira J, Campos J, Qvit N, Qi X, Bozi L, Bechara L, et al.
Nat Commun
. 2024 Apr;
15(1):2889.
PMID: 38570501
No abstract available.
3.
Vilela W, Ramalho L, Bechara L, Cabral-Costa J, Serna J, Kowaltowski A, et al.
J Bioenerg Biomembr
. 2024 Feb;
56(2):87-99.
PMID: 38374292
High-fat diet-induced metabolic changes are not restricted to the onset of cardiovascular diseases, but also include effects on brain functions related to learning and memory. This study aimed to evaluate...
4.
4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification
Kiyuna L, Candido D, Bechara L, Jesus I, Ramalho L, Krum B, et al.
Eur Heart J
. 2023 Nov;
44(44):4696-4712.
PMID: 37944136
Background And Aims: Developing novel therapies to battle the global public health burden of heart failure remains challenging. This study investigates the underlying mechanisms and potential treatment for 4-hydroxynonenal (4-HNE)...
5.
Ribeiro F, Alves P, Bechara L, Ferreira J, Labeit S, Moriscot A
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835047
In clinical conditions such as diaphragm paralysis or mechanical ventilation, disuse-induced diaphragmatic dysfunction (DIDD) is a condition that poses a threat to life. MuRF1 is a key E3-ligase involved in...
6.
Tostes K, Dos Santos A, Alves L, Bechara L, Marascalchi R, Macabelli C, et al.
Autophagy
. 2022 Feb;
18(10):2397-2408.
PMID: 35220898
Mutations in the mitochondrial genome (mtDNA) are ubiquitous in humans and can lead to a broad spectrum of disorders. However, due to the presence of multiple mtDNA molecules in the...
7.
Parada C, de Oliveira I, Gewehr M, Machado-Neto J, Lima K, Eichler R, et al.
Cells
. 2022 Feb;
11(3).
PMID: 35159195
Intracellular peptides (InPeps) generated by proteasomes were previously suggested as putative natural regulators of protein-protein interactions (PPI). Here, the main aim was to investigate the intracellular effects of intracellular peptide...
8.
Alves C, Eichelberger E, das Neves W, Ribeiro M, Bechara L, Voltarelli V, et al.
FASEB J
. 2021 Jun;
35(7):e21714.
PMID: 34118107
We tested the hypothesis that cancer cachexia progression would induce oxidative post-translational modifications (Ox-PTMs) associated with skeletal muscle wasting, with different responses in muscles with the prevalence of glycolytic and...
9.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
10.
Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN
Alves C, das Neves W, de Almeida N, Eichelberger E, Jannig P, Voltarelli V, et al.
Mol Metab
. 2020 May;
39:101012.
PMID: 32408015
Objective: We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods: We used multiple in vivo and in vitro methods to...