Luisa Lo Iacono
Overview
Explore the profile of Luisa Lo Iacono including associated specialties, affiliations and a list of published articles.
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28
Citations
430
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Recent Articles
1.
Ielpo D, Guzzo S, Porcheddu G, Viscomi M, Catale C, Reverte I, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(32):e2301730120.
PMID: 37523544
The brain employs distinct circuitries to encode positive and negative valence stimuli, and dysfunctions of these neuronal circuits have a key role in the etiopathogenesis of many psychiatric disorders. The...
2.
DAddario S, Municchi D, Mancini C, Ielpo D, Babicola L, Di Segni M, et al.
J Affect Disord
. 2022 Nov;
322:277-288.
PMID: 36414112
Background: Exposure to early life adversities (ELA) can influence a plethora of biological mechanisms leading to stress-related disorders later in life through epigenetic mechanisms, such as microRNAs (miRs). MiR-34 is...
3.
Catale C, Martini A, Piscitelli R, Senzasono B, Lo Iacono L, Mercuri N, et al.
Eur J Neurosci
. 2022 Sep;
56(10):5763-5783.
PMID: 36117291
Child maltreatment disrupts trajectories of brain development, but the underlying pathways are unclear. Stressful stimuli in early life interfere with maturation of local inhibitory circuitry and deposition of perineuronal nets...
4.
Catale C, Lo Iacono L, Martini A, Heil C, Guatteo E, Mercuri N, et al.
Mol Neurobiol
. 2022 Apr;
59(6):3913-3932.
PMID: 35435618
Early life stress (ELS) is known to modify trajectories of brain dopaminergic development, but the mechanisms underlying have not been determined. ELS perturbs immune system and microglia reactivity, and inflammation...
5.
Psychobiological Consequences of Childhood Sexual Abuse: Current Knowledge and Clinical Implications
Lo Iacono L, Trentini C, Carola V
Front Neurosci
. 2021 Dec;
15:771511.
PMID: 34924938
A large body of research has documented the long-term harms of childhood sexual abuse (CSA) on an individual's emotional-adaptive function and mental health. Recent studies have also provided evidence of...
6.
Lo Iacono L, Mancini C, Babicola L, Pietrosanto M, Di Segni M, DAddario S, et al.
Neurobiol Stress
. 2021 Oct;
15:100406.
PMID: 34660854
Early life experiences that affect the attachment bond formation can alter developmental trajectories and result in pathological outcomes in a sex-related manner. However, the molecular basis of sex differences is...
7.
Andolina D, Savi M, Ielpo D, Barbetti M, Bocchi L, Stilli D, et al.
Stress
. 2021 Jul;
24(5):621-634.
PMID: 34227918
This study investigated epigenetic risk factors that may contribute to stress-related cardiac disease in a rodent model. Experiment 1 was designed to evaluate the expression of microRNA-34a (miR-34a), a known...
8.
Lo Iacono L, Ielpo D, Parisi C, Napoli G, Accoto A, Di Segni M, et al.
Neuropharmacology
. 2021 Apr;
190:108559.
PMID: 33845072
Selective serotonin reuptake inhibitors (SSRIs) are designed to improve mood by raising extracellular serotonin levels through the blockade of the serotonin transporter. However, they exhibit a slow onset of action,...
9.
Catale C, Bussone S, Lo Iacono L, Viscomi M, Palacios D, Troisi A, et al.
Neurobiol Stress
. 2020 Dec;
13:100249.
PMID: 33344704
The existence of a proportional relationship between the number of early-life stress (ELS) events experienced and the impoverishment of child mental health has been hypothesized. However, different types of ELS...
10.
Lo Iacono L, Bussone S, Andolina D, Tambelli R, Troisi A, Carola V
J Affect Disord
. 2020 Sep;
276:351-360.
PMID: 32871665
Background: The syndromic diagnosis of major depressive disorder (MDD) is associated with individual differences in prognosis, course, treatment response, and outcome. There is evidence that patients with a history to...