Luis Miguel Guachalla
Overview
Explore the profile of Luis Miguel Guachalla including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
14
Citations
429
Followers
0
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Recent Articles
1.
Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla L, Lechel A, et al.
Nat Cell Biol
. 2021 Jan;
23(3):292.
PMID: 33510409
No abstract available.
2.
Guachalla L, Ju Z, Koziel R, von Figura G, Song Z, Fusser M, et al.
Aging (Albany NY)
. 2019 Dec;
11(23):11793-11794.
PMID: 31879376
No abstract available.
3.
Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, et al.
Cell
. 2017 Sep;
158(6):1444.
PMID: 28915370
No abstract available.
4.
Szijarto V, Guachalla L, Hartl K, Varga C, Banerjee P, Stojkovic K, et al.
Int J Med Microbiol
. 2016 Jan;
306(2):89-98.
PMID: 26723873
Klebsiella pneumoniae ST258 is a globally disseminated, extremely drug resistant, nosocomial clone with limited treatment options. We show that the vast majority of ST258 isolates express modified d-galactan-I lipopolysaccharide O-antigen,...
5.
Li T, Shi Y, Wang P, Guachalla L, Sun B, Joerss T, et al.
EMBO J
. 2015 Mar;
34(12):1630-47.
PMID: 25770585
Nonsense-mediated mRNA decay (NMD) is a post-transcriptional mechanism that targets aberrant transcripts and regulates the cellular RNA reservoir. Genetic modulation in vertebrates suggests that NMD is critical for cellular and...
6.
Missios P, Zhou Y, Guachalla L, von Figura G, Wegner A, Chakkarappan S, et al.
Nat Commun
. 2014 Sep;
5:4924.
PMID: 25233189
DNA damage and telomere dysfunction shorten organismal lifespan. Here we show that oral glucose administration at advanced age increases health and lifespan of telomere dysfunctional mice. The study reveals that...
7.
Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, et al.
Cell
. 2012 Mar;
148(5):1001-14.
PMID: 22385964
Checkpoints that limit stem cell self-renewal in response to DNA damage can contribute to cancer protection but may also promote tissue aging. Molecular components that control stem cell responses to...
8.
Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla L, Lechel A, et al.
Nat Cell Biol
. 2011 Dec;
14(1):73-9.
PMID: 22138576
The tumour suppressor p53 activates Puma-dependent apoptosis and p21-dependent cell-cycle arrest in response to DNA damage. Deletion of p21 improved stem-cell function and organ maintenance in progeroid mice with dysfunctional...
9.
von Figura G, Wagner M, Nalapareddy K, Hartmann D, Kleger A, Guachalla L, et al.
PLoS One
. 2011 Mar;
6(2):e17122.
PMID: 21364961
Introduction: Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence. Shortening of telomeres has been shown...
10.