Luis Menendez
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Explore the profile of Luis Menendez including associated specialties, affiliations and a list of published articles.
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43
Citations
492
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Recent Articles
1.
Gonzalez-Rodriguez S, Sordo-Bahamonde C, Alvarez-Artime A, Baamonde A, Menendez L
J Neuroimmune Pharmacol
. 2024 Aug;
19(1):44.
PMID: 39152360
The systemic administration of interleukin-16 (IL-16, 3-30 ng/kg) induced thermal hyperalgesia in mice, that was prevented by the acute injection of an anti-CD4 antibody (1 µg/kg), the depletion of circulating...
2.
Baamonde A, Menendez L
J Neurosci Methods
. 2023 Jan;
386:109783.
PMID: 36610617
Pharmacological assays based on the measurement of nociceptive responses in laboratory animals are a fundamental tool to assess analgesic strategies. During our experience with this type of experiments, we have...
3.
Gonzalez-Rodriguez S, Lorenzo-Herrero S, Sordo-Bahamonde C, Hidalgo A, Gonzalez S, Menendez L, et al.
Life Sci
. 2022 Jan;
291:120302.
PMID: 34999112
Aims: To explore the mechanisms involved in the transformation of analgesia produced by low doses of CCL4 (pg/kg) to hyperalgesia when higher doses (ng/kg) are administered to mice. Main Methods:...
4.
Garcia-Dominguez M, Gonzalez-Rodriguez S, Hidalgo A, Baamonde A, Menendez L
Fundam Clin Pharmacol
. 2021 Apr;
35(6):1109-1118.
PMID: 33905573
Background: The chemokine CC motif ligand 1 (CCL1) participates in immune cell recruitment and, as other chemokines, is also involved in nociceptive processing. In contrast with previous reports indicating its...
5.
Baamonde A, Menendez L, Gonzalez-Rodriguez S, Lastra A, Seitz V, Stein C, et al.
Sci Rep
. 2020 Oct;
10(1):18599.
PMID: 33122720
The newly designed fentanyl derivative [( ±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide] (NFEPP) was recently shown to produce analgesia selectively via peripheral mu-opioid receptors (MOR) at acidic pH in rat inflamed tissues. Here, we...
6.
Aguirre A, Gonzalez-Rodriguez S, Garcia-Dominguez M, Lastra A, Gutierrez-Fernandez A, Hidalgo A, et al.
Biochem Pharmacol
. 2020 Mar;
175:113903.
PMID: 32156658
As recently described, the administration of extremely low doses (pg/kg) of CCL4 (Macrophage inflammatory protein 1β, MIP-1β) can induce antinociceptive effects in mice (García-Domínguez et al., 2019b). We describe here...
7.
Garcia-Dominguez M, Aguirre A, Lastra A, Hidalgo A, Baamonde A, Menendez L
Cell Mol Neurobiol
. 2019 Jun;
39(8):1115-1124.
PMID: 31203533
Apart from its involvement in immune functions, the chemokine CCL1 can participate in the modulation of nociceptive processing. Previous studies have demonstrated the hypernociceptive effect produced by CCL1 in the...
8.
Garcia-Dominguez M, Lastra A, Folgueras A, Cernuda-Cernuda R, Fernandez-Garcia M, Hidalgo A, et al.
Mol Neurobiol
. 2018 Jun;
56(3):1578-1595.
PMID: 29907903
In the present study, we characterize the antinociceptive effects produced by the chemokine CCL4 in mice. The intraplantar administration of very low doses of CCL4 (0.1-3 pg) produced bilateral antinociception...
9.
Gonzalez-Rodriguez S, Poras H, Menendez L, Lastra A, Ouimet T, Fournie-Zaluski M, et al.
Scand J Pain
. 2017 Aug;
14:25-38.
PMID: 28850427
Background: The first line pharmacological treatment of cancer pain is morphine and surrogates but a significant pain relief and a reduction of the side-effects of these compounds makes it necessary...
10.
Gonzalez-Rodriguez S, Alvarez M, Garcia-Dominguez M, Lastra A, Cernuda-Cernuda R, Folgueras A, et al.
Brain Behav Immun
. 2017 Jan;
62:151-161.
PMID: 28126501
We show here that the intraplantar administration of CCL5 in mice produces hyperalgesia at low doses but activates compensatory antinociceptive mechanisms at doses slightly higher. Thus, the injection of 3-10ng...