Luigi A De Girolamo
Overview
Explore the profile of Luigi A De Girolamo including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
9
Citations
144
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0
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Recent Articles
1.
Leston Pinilla L, Ugun-Klusek A, Rutella S, De Girolamo L
Biology (Basel)
. 2021 Aug;
10(8).
PMID: 34439955
Hypoxia is a condition characterized by insufficient tissue oxygenation, which results in impaired oxidative energy production. A reduction in cellular oxygen levels induces the stabilization of hypoxia inducible factor α...
2.
Chemmarappally J, Pegram H, Abeywickrama N, Fornari E, Hargreaves A, De Girolamo L, et al.
Sci Rep
. 2020 Feb;
10(1):2767.
PMID: 32066745
Current therapeutic strategies for Parkinson's disease (PD) aim to delay progression or replace damaged neurons by restoring the original neuronal structures. The poor regenerative capacity of neural tissue highlights the...
3.
Ponniah M, Billett E, De Girolamo L
Chem Res Toxicol
. 2015 Aug;
28(9):1693-703.
PMID: 26247420
Bisphenol A (BPA) is ubiquitous in the environment and is reported to be present at high concentrations in placental tissue, where its presence raises concerns over its potential to disrupt...
4.
Fitzgerald J, Ugun-Klusek A, Allen G, De Girolamo L, Hargreaves I, Ufer C, et al.
FASEB J
. 2013 Sep;
28(1):218-29.
PMID: 24051032
The study examined how the mitochondrial enzyme monoamine oxidase-A (MAO-A), which produces hydrogen peroxide as a catalytic by-product, influences death and survival mechanisms. Targeted microRNA (miRNA) was used to stably...
5.
Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition
Burte F, De Girolamo L, Hargreaves A, Billett E
J Proteome Res
. 2011 Feb;
10(4):1974-86.
PMID: 21322648
Increasing evidence points to mitochondrial dysfunction in Parkinson's disease (PD) associated with complex I dysfunction, but the exact pathways which lead to cell death have not been resolved. 2D-gel electrophoresis...
6.
Caneda-Ferron B, De Girolamo L, Costa T, Beck K, Layfield R, Billett E
J Neurochem
. 2007 Nov;
105(1):225-38.
PMID: 18021296
Mitochondrial impairment, glutathione depletion and oxidative stress have been implicated in the pathogenesis of Parkinson's disease (PD), linked recently to proteasomal dysfunction. Our study analysed how these factors influence the...
7.
Fitzgerald J, Ufer C, De Girolamo L, Kuhn H, Billett E
J Neurochem
. 2007 Sep;
103(6):2189-99.
PMID: 17883400
Monoamine oxidases (MAOs) are mitochondrial enzymes which control the levels of neurotransmitters in the brain and dietary amines in peripheral tissues via oxidative deamination. MAO has also been implicated in...
8.
Beck K, De Girolamo L, Griffin M, Billett E
Neurosci Lett
. 2006 Aug;
405(1-2):46-51.
PMID: 16876317
Tissue transglutaminase (TG2) can induce post-translational modification of proteins, resulting in protein cross-linking or incorporation of polyamines into substrates, and can also function as a signal transducing G protein. The...
9.
De Girolamo L, Billett E
J Neurosci Res
. 2006 Feb;
83(4):680-93.
PMID: 16447269
The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes selective degeneration of dopaminergic neurons in which the c-Jun NH2-terminal kinase (JNK) signalling cascade has been implicated. We have employed a differentiated mouse neuroblastoma N2a...