Lucy Cassar
Overview
Explore the profile of Lucy Cassar including associated specialties, affiliations and a list of published articles.
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5
Citations
77
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Recent Articles
1.
Cassar L, Nicholls C, Pinto A, Chen R, Wang L, Li H, et al.
Protein Cell
. 2016 Oct;
8(1):39-54.
PMID: 27696331
Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. Here we...
2.
Cassar L, Li H, Jiang F, Liu J
Mol Cell Endocrinol
. 2010 Feb;
320(1-2):97-105.
PMID: 20138964
Recent studies suggest that transforming growth factor beta (TGF-beta) inhibits telomerase activity by repression of the telomerase reverse transcriptase (TERT) gene. In this report, we show that TGF-beta induces TERT...
3.
Cassar L, Nicholls C, Pinto A, Li H, Liu J
FASEB J
. 2009 Feb;
23(6):1880-92.
PMID: 19193721
Human telomerase reverse transcriptase (hTERT) is central to maintain telomeres for continuous cell proliferation, but it remains unknown how extracellular cues regulate telomerase maintenance of telomeres. Here we report that...
4.
Cassar L, Li H, Pinto A, Nicholls C, Bayne S, Liu J
Cancer Res
. 2008 Nov;
68(22):9157-66.
PMID: 19010887
Telomere maintenance is critical in tumor cell immortalization. Here, we report that the cytokine bone morphogenetic protein-7 (BMP7) inhibits telomerase activity that is required for telomere maintenance in cervical cancer...
5.
Liu J, Cassar L, Pinto A, Li H
Cell Res
. 2006 Oct;
16(10):809-17.
PMID: 17016469
Nasopharyngeal carcinoma (NPC) is a common cancer in Southern China and Southeast Asia. The disease is a poorly differentiated carcinoma without effective cure, and the mechanism underlying its development remains...