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Luckio F Owuocha

Explore the profile of Luckio F Owuocha including associated specialties, affiliations and a list of published articles. Areas
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Citations 7
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Recent Articles
1.
Samarakoon V, Owuocha L, Hammond J, Mitchum M, Beamer L
Biochem J . 2024 Oct; 481(21):1557-1568. PMID: 39373197
The enzyme serine hydroxymethyltransferase (SHMT) plays a key role in folate metabolism and is conserved in all kingdoms of life. SHMT is a pyridoxal 5'-phosphate (PLP) - dependent enzyme that...
2.
Owuocha L, Mitchum M, Beamer L
Front Plant Sci . 2024 Sep; 15:1451839. PMID: 39224855
Tetrahydrofolate and its derivatives participate in one-carbon transfer reactions in all organisms. The cellular form of tetrahydrofolate (THF) is modified by multiple glutamate residues and polyglutamylation plays a key role...
3.
Korasick D, Owuocha L, Kandoth P, Tanner J, Mitchum M, Beamer L
FEBS J . 2023 Oct; 291(2):323-337. PMID: 37811683
Two amino acid variants in soybean serine hydroxymethyltransferase 8 (SHMT8) are associated with resistance to the soybean cyst nematode (SCN), a devastating agricultural pathogen with worldwide economic impacts on soybean...
4.
Radenkovic S, Ligezka A, Mokashi S, Driesen K, Dukes-Rimsky L, Preston G, et al.
Cell Rep Med . 2023 May; 4(6):101056. PMID: 37257447
Abnormal polyol metabolism is predominantly associated with diabetes, where excess glucose is converted to sorbitol by aldose reductase (AR). Recently, abnormal polyol metabolism has been implicated in phosphomannomutase 2 congenital...
5.
Stiers K, Owuocha L, Beamer L
Acta Crystallogr F Struct Biol Commun . 2022 May; 78(Pt 5):200-209. PMID: 35506765
Phosphoglucomutase 1 (PGM1) plays a central role in glucose homeostasis in human cells. Missense variants of this enzyme cause an inborn error of metabolism, which is categorized as a congenital...