Lucinda L Fulton
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Explore the profile of Lucinda L Fulton including associated specialties, affiliations and a list of published articles.
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30
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14001
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Recent Articles
1.
Jarvis E, Formenti G, Rhie A, Guarracino A, Yang C, Wood J, et al.
Nature
. 2022 Oct;
611(7936):519-531.
PMID: 36261518
The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society. However, it still has many gaps and errors, and...
2.
Faber Z, Chen X, Gedman A, Boggs K, Cheng J, Ma J, et al.
Nat Genet
. 2016 Nov;
48(12):1551-1556.
PMID: 27798625
Acute myeloid leukemia (AML) comprises a heterogeneous group of leukemias frequently defined by recurrent cytogenetic abnormalities, including rearrangements involving the core-binding factor (CBF) transcriptional complex. To better understand the genomic...
3.
Cui J, Diogo D, Stahl E, Canhao H, Mariette X, Greenberg J, et al.
Arthritis Rheumatol
. 2016 Oct;
69(4):735-741.
PMID: 27788309
Objective: In many rheumatoid arthritis (RA) patients, disease is controlled with anti-tumor necrosis factor (anti-TNF) biologic therapies. However, in a significant number of patients, the disease fails to respond to...
4.
Diogo D, Bastarache L, Liao K, Graham R, Fulton R, Greenberg J, et al.
PLoS One
. 2015 Apr;
10(4):e0122271.
PMID: 25849893
Despite the success of genome-wide association studies (GWAS) in detecting a large number of loci for complex phenotypes such as rheumatoid arthritis (RA) susceptibility, the lack of information on the...
5.
Staudova B, Strouhal M, Zobanikova M, Cejkova D, Fulton L, Chen L, et al.
PLoS Negl Trop Dis
. 2014 Nov;
8(11):e3261.
PMID: 25375929
Background: T. pallidum subsp. endemicum (TEN) is the causative agent of bejel (also known as endemic syphilis). Clinical symptoms of syphilis and bejel are overlapping and the epidemiological context is...
6.
Hughes A, Magrini V, Demeter R, Miller C, Fulton R, Fulton L, et al.
PLoS Genet
. 2014 Jul;
10(7):e1004462.
PMID: 25010716
Next-generation sequencing has been used to infer the clonality of heterogeneous tumor samples. These analyses yield specific predictions-the population frequency of individual clones, their genetic composition, and their evolutionary relationships-which...
7.
Wu G, Diaz A, Paugh B, Rankin S, Ju B, Li Y, et al.
Nat Genet
. 2014 Apr;
46(5):444-450.
PMID: 24705251
Pediatric high-grade glioma (HGG) is a devastating disease with a less than 20% survival rate 2 years after diagnosis. We analyzed 127 pediatric HGGs, including diffuse intrinsic pontine gliomas (DIPGs)...
8.
Parker M, Mohankumar K, Punchihewa C, Weinlich R, Dalton J, Li Y, et al.
Nature
. 2014 Feb;
506(7489):451-5.
PMID: 24553141
Members of the nuclear factor-κB (NF-κB) family of transcriptional regulators are central mediators of the cellular inflammatory response. Although constitutive NF-κB signalling is present in most human tumours, mutations in...
9.
McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, et al.
Oncotarget
. 2014 Feb;
5(2):438-50.
PMID: 24509483
Retinoblastoma is a rare childhood cancer of the developing retina. Most retinoblastomas initiate with biallelic inactivation of the RB1 gene through diverse mechanisms including point mutations, nucleotide insertions, deletions, loss...
10.
Service S, Teslovich T, Fuchsberger C, Ramensky V, Yajnik P, Koboldt D, et al.
PLoS Genet
. 2014 Feb;
10(1):e1004147.
PMID: 24497850
Genome-wide association studies (GWAS) have identified >500 common variants associated with quantitative metabolic traits, but in aggregate such variants explain at most 20-30% of the heritable component of population variation...