Lucile Dollet
Overview
Explore the profile of Lucile Dollet including associated specialties, affiliations and a list of published articles.
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15
Citations
521
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Recent Articles
1.
Sass F, Ma T, Ekberg J, Kirigiti M, Urena M, Dollet L, et al.
Nature
. 2024 Nov;
635(8040):987-1000.
PMID: 39537932
The combination of decreasing food intake and increasing energy expenditure represents a powerful strategy for counteracting cardiometabolic diseases such as obesity and type 2 diabetes. Yet current pharmacological approaches require...
2.
Pendergrast L, Ashcroft S, Ehrlich A, Treebak J, Krook A, Dollet L, et al.
Metabolism
. 2024 Mar;
155:155834.
PMID: 38479569
Background: Circadian disruption is widespread and increases the risk of obesity. Timing of therapeutic interventions may promote coherent and efficient gating of metabolic processes and restore energy homeostasis. Aim: To...
3.
Dollet L, Lundell L, Chibalin A, Pendergrast L, Pillon N, Lansbury E, et al.
Cell Rep Med
. 2023 Dec;
5(1):101348.
PMID: 38151020
The discovery of exercise-regulated circulatory factors has fueled interest in organ crosstalk, especially between skeletal muscle and adipose tissue, and the role in mediating beneficial effects of exercise. We studied...
4.
Pham T, Dollet L, Ali M, Raun S, Moller L, Jafari A, et al.
Sci Adv
. 2023 Aug;
9(32):eadf7119.
PMID: 37556547
Obesity and type 2 diabetes (T2D) are growing health challenges with unmet treatment needs. Traf2- and NCK-interacting protein kinase (TNIK) is a recently identified obesity- and T2D-associated gene with unknown...
5.
Pendergrast L, Lundell L, Ehrlich A, Ashcroft S, Schonke M, Basse A, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(8):e2218510120.
PMID: 36780527
The circadian clock is a cell-autonomous transcription-translation feedback mechanism that anticipates and adapts physiology and behavior to different phases of the day. A variety of factors including hormones, temperature, food-intake,...
6.
Dollet L, Kuefner M, Caria E, Rizo-Roca D, Pendergrast L, Abdelmoez A, et al.
Diabetes
. 2022 Jan;
71(4):624-636.
PMID: 35040927
Dysregulation of skeletal muscle metabolism influences whole-body insulin sensitivity and glucose homeostasis. We hypothesized that type 2 diabetes-associated alterations in the plasma metabolome directly contribute to skeletal muscle immunometabolism and...
7.
Gabriel B, Altintas A, Smith J, Sardon-Puig L, Zhang X, Basse A, et al.
Sci Adv
. 2021 Oct;
7(43):eabi9654.
PMID: 34669477
Circadian rhythms are generated by an autoregulatory feedback loop of transcriptional activators and repressors. Circadian rhythm disruption contributes to type 2 diabetes (T2D) pathogenesis. We elucidated whether altered circadian rhythmicity...
8.
Dollet L, Pendergrast L, Zierath J
Curr Opin Lipidol
. 2020 Dec;
32(1):16-23.
PMID: 33278080
Purpose Of Review: The aim of this review is to present the latest findings on the role of the circadian clock in the control of metabolism, and the therapeutic potential...
9.
Pillon N, Gabriel B, Dollet L, Smith J, Sardon Puig L, Botella J, et al.
Nat Commun
. 2020 Jan;
11(1):470.
PMID: 31980607
The molecular mechanisms underlying the response to exercise and inactivity are not fully understood. We propose an innovative approach to profile the skeletal muscle transcriptome to exercise and inactivity using...
10.
Petrus P, Lecoutre S, Dollet L, Wiel C, Sulen A, Gao H, et al.
Cell Metab
. 2019 Dec;
31(2):375-390.e11.
PMID: 31866443
While obesity and associated metabolic complications are linked to inflammation of white adipose tissue (WAT), the causal factors remain unclear. We hypothesized that the local metabolic environment could be an...