Lucien C Manchester
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Explore the profile of Lucien C Manchester including associated specialties, affiliations and a list of published articles.
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53
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3862
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Recent Articles
1.
Tan D, Manchester L, Qin L, Reiter R
Int J Mol Sci
. 2016 Dec;
17(12).
PMID: 27999288
Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation is supported by the recent discovery that aralkylamine -acetyltransferase/serotonin -acetyltransferase (AANAT/SNAT) is localized in mitochondria of oocytes and...
2.
Tan D, Hardeland R, Back K, Manchester L, Alatorre-Jimenez M, Reiter R
J Pineal Res
. 2016 Apr;
61(1):27-40.
PMID: 27112772
Melatonin is a phylogenetically ancient molecule. It is ubiquitously present in almost all organisms from primitive photosynthetic bacteria to humans. Its original primary function is presumable to be that of...
3.
Tan D, Manchester L, Reiter R
Med Hypotheses
. 2016 Jan;
86:3-9.
PMID: 26804589
Pineal gland is an important organ for the regulation of the bio-clock in all vertebrate species. Its major secretory product is melatonin which is considered as the chemical expression of...
4.
Tan D, Manchester L, Esteban-Zubero E, Zhou Z, Reiter R
Molecules
. 2015 Oct;
20(10):18886-906.
PMID: 26501252
Melatonin is a tryptophan-derived molecule with pleiotropic activities. It is present in almost all or all organisms. Its synthetic pathway depends on the species in which it is measured. For...
5.
Manchester L, Coto-Montes A, Boga J, Andersen L, Zhou Z, Galano A, et al.
J Pineal Res
. 2015 Aug;
59(4):403-19.
PMID: 26272235
Melatonin is remarkably functionally diverse with actions as a free radical scavenger and antioxidant, circadian rhythm regulator, anti-inflammatory and immunoregulating molecule, and as an oncostatic agent. We hypothesize that the...
6.
Tan D, Korkmaz A, Reiter R, Manchester L
J Pineal Res
. 2014 Sep;
57(4):381-4.
PMID: 25262626
The purpose of this report is to emphasize the potential utility for the use of melatonin in the treatment of individuals who are infected with the Ebola virus. The pathological...
7.
Tan D, Zheng X, Kong J, Manchester L, Hardeland R, Kim S, et al.
Int J Mol Sci
. 2014 Sep;
15(9):15858-90.
PMID: 25207599
Melatonin and melatonin isomers exist and/or coexist in living organisms including yeasts, bacteria and plants. The levels of melatonin isomers are significantly higher than that of melatonin in some plants...
8.
Tan D, Zanghi B, Manchester L, Reiter R
J Pineal Res
. 2014 Jun;
57(2):213-8.
PMID: 24942090
Melatonin has been identified in primitive photosynthetic bacteria, fungi, plants, and animals including humans. Vegetables, fruits, cereals, wine, and beers all contain melatonin. However, the melatonin content in meats has...
9.
Reiter R, Rosales-Corral S, Manchester L, Liu X, Tan D
Curr Pharm Des
. 2013 Nov;
20(30):4788-801.
PMID: 24251672
Melatonin is a widely-produced and ubiquitously-distributed molecule with multiple critical functions in all organs and organisms. These functions are mediated by both receptor-mediated and receptor-independent actions of the indole. This...
10.
Reiter R, Tan D, Manchester L, Korkmaz A, Fuentes-Broto L, Hardman W, et al.
Cancer Invest
. 2013 Jun;
31(6):365-73.
PMID: 23758186
It was investigated whether a standard mouse diet (AIN-76A) supplemented with walnuts reduced the establishment and growth of LNCaP human prostate cancer cells in nude (nu/nu) mice. The walnut-enriched diet...