Lucie Deruyter
Overview
Explore the profile of Lucie Deruyter including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
295
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Recent Articles
1.
Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice
Silva Angulo F, Joseph C, Delval L, Deruyter L, Heumel S, Bicharel M, et al.
Cell Rep
. 2025 Feb;
44(2):115273.
PMID: 39908141
Circadian rhythms control the diurnal nature of many physiological, metabolic, and immune processes. We hypothesized that age-related impairments in circadian rhythms are associated with high susceptibility to bacterial respiratory tract...
2.
Chollet L, Heumel S, Deruyter L, Bouilloux F, Delval L, Robert V, et al.
Front Immunol
. 2024 Apr;
15:1347676.
PMID: 38590519
The gut-lung axis is critical during viral respiratory infections such as influenza. Gut dysbiosis during infection translates into a massive drop of microbially produced short-chain fatty acids (SCFAs). Among them,...
3.
Heumel S, de Rezende Rodovalho V, Urien C, Specque F, Rodrigues P, Robil C, et al.
Gut Microbes
. 2024 Mar;
16(1):2325067.
PMID: 38445660
The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associated...
4.
Cobanoglu O, Delval L, Ferrari D, Deruyter L, Heumel S, Wolowczuk I, et al.
Aging Cell
. 2023 Nov;
22(12):e14007.
PMID: 37997569
The age-related decline in immunity reduces the effectiveness of vaccines in older adults. Immunosenescence is associated with chronic, low-grade inflammation, and the accumulation of senescent cells. The latter express Bcl-2...
5.
Delval L, Hantute-Ghesquier A, Sencio V, Flaman J, Robil C, Silva Angulo F, et al.
Nat Aging
. 2023 Jul;
3(7):829-845.
PMID: 37414987
Older age is one of the strongest risk factors for severe COVID-19. In this study, we determined whether age-associated cellular senescence contributes to the severity of experimental COVID-19. Aged golden...
6.
Briand F, Sencio V, Robil C, Heumel S, Deruyter L, Machelart A, et al.
Viruses
. 2022 Sep;
14(9).
PMID: 36146875
Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable...
7.
Sencio V, Benech N, Robil C, Deruyter L, Heumel S, Machelart A, et al.
Gut Microbes
. 2022 Jul;
14(1):2100200.
PMID: 35830432
Obese patientss with nonalcoholic steatohepatitis (NASH) are particularly prone to developing severe forms of coronavirus disease 19 (COVID-19). The gut-to-lung axis is critical during viral infections of the respiratory tract,...
8.
Belouzard S, Machelart A, Sencio V, Vausselin T, Hoffmann E, Deboosere N, et al.
PLoS Pathog
. 2022 May;
18(5):e1010498.
PMID: 35587469
Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those...
9.
Verstraeten S, Sencio V, Raise A, Huillet E, Layec S, Deruyter L, et al.
Nutrients
. 2022 Apr;
14(7).
PMID: 35406091
The expanding knowledge on the systemic influence of the human microbiome suggests that fecal samples are underexploited sources of new beneficial strains for extra-intestinal health. We have recently shown that...
10.
Machado M, Patente T, Rouille Y, Heumel S, Melo E, Deruyter L, et al.
Front Immunol
. 2022 Feb;
13:773261.
PMID: 35126390
Short-chain fatty acids (SCFAs) are metabolites produced mainly by the gut microbiota with a known role in immune regulation. Acetate, the major SCFA, is described to disseminate to distal organs...