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Luciana C Caperuto

Explore the profile of Luciana C Caperuto including associated specialties, affiliations and a list of published articles. Areas
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Citations 390
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Recent Articles
1.
Banzato R, Pinheiro N, Olivo C, Santana F, Lopes F, Caperuto L, et al.
Sci Rep . 2021 Aug; 11(1):15918. PMID: 34354132
Acetylcholine (ACh), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. ACh is also involved in a non-neuronal mechanism that modulates the innate immune response....
2.
Santana F, Da Silva R, Ponci V, Pinheiro A, Olivo C, Caperuto L, et al.
Biochem Pharmacol . 2020 Jul; 180:114175. PMID: 32717226
Background: Eugenol, a common phenylpropanoid derivative found in different plant species, has well-described anti-inflammatory effects associated with the development of occupational hypersensitive asthma. Dehydrodieugenol, a dimeric eugenol derivative, exhibits anti-inflammatory...
3.
Pinheiro N, Miranda C, Santana F, Bittencourt-Mernak M, Arantes-Costa F, Olivo C, et al.
Eur J Pharmacol . 2020 Jul; 882:173239. PMID: 32619677
The cholinergic anti-inflammatory pathway has been shown to regulate lung inflammation and cytokine release in acute models of inflammation, mainly via α7 nicotinic receptor (α7nAChR). We aimed to evaluate the...
4.
Santana F, Da Silva R, Grecco S, Pinheiro A, Caperuto L, Arantes-Costa F, et al.
Mediators Inflamm . 2019 Oct; 2019:1356356. PMID: 31565031
Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid...
5.
Bittencourt-Mernak M, Pinheiro N, Santana F, Guerreiro M, Saraiva-Romanholo B, Grecco S, et al.
Am J Physiol Lung Cell Mol Physiol . 2016 Nov; 312(2):L217-L230. PMID: 27881407
Sakuranetin is the main isolate flavonoid from () leaves and exhibits anti-inflammatory and antioxidative activities. Acute respiratory distress syndrome is an acute failure of the respiratory system for which effective...
6.
Pinheiro N, Santana F, Almeida R, Guerreiro M, Martins M, Caperuto L, et al.
FASEB J . 2016 Oct; 31(1):320-332. PMID: 27729414
Nicotinic α-7 acetylcholine receptor (nAChRα7) is a critical regulator of cholinergic anti-inflammatory actions in several diseases, including acute respiratory distress syndrome (ARDS). Given the potential importance of α7nAChR as a...
7.
Barrosa K, Mecchi M, Rando D, Ferreira A, Sartorelli P, Valle M, et al.
Chem Biol Interact . 2016 Sep; 258:245-56. PMID: 27645309
Despite its common use, the synthetic glucocorticoid dexamethasone can cause several adverse effects, such as diabetes and insulin-related metabolic impairment. Thus, research on molecules that could provide the same anti-inflammatory...
8.
Taguchi L, Pinheiro N, Olivo C, Choqueta-Toledo A, Grecco S, Lopes F, et al.
Respir Res . 2015 Sep; 16:113. PMID: 26381862
No abstract available.
9.
Taguchi L, Pinheiro N, Olivo C, Choqueta-Toledo A, Grecco S, Lopes F, et al.
Respir Res . 2015 Jul; 16:79. PMID: 26122092
Background: Pulmonary emphysema is characterized by irreversible airflow obstruction, inflammation, oxidative stress imbalance and lung remodeling, resulting in reduced lung function and a lower quality of life. Flavonoids are plant...
10.
Pinheiro N, Miranda C, Perini A, Camara N, Costa S, Alonso-Vale M, et al.
PLoS One . 2015 Mar; 10(3):e0120441. PMID: 25816137
Acetylcholine (ACh) plays a crucial role in physiological responses of both the central and the peripheral nervous system. Moreover, ACh was described as an anti-inflammatory mediator involved in the suppression...