Lucian Farcal
Overview
Explore the profile of Lucian Farcal including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
191
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0
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Recent Articles
1.
Hernandez-Jerez A, Bennekou S, Hoogenboom L, Mcardle H, Pieper C, Schwerdtle T, et al.
EFSA J
. 2024 Dec;
22(12):e9153.
PMID: 39691503
This Scientific Report was carried out in the context of the self-task mandate (M-2023-00097) of the EFSA's Scientific Committee on 'Guidance on the use of biomarkers of effect in regulatory...
2.
Hardy B, Mohoric T, Exner T, Dokler J, Brajnik M, Bachler D, et al.
Toxicol In Vitro
. 2024 Jul;
100:105903.
PMID: 39047988
The EU-ToxRisk project (2016-2021) was a large European project working towards shifting toxicological testing away from animal tests, towards a toxicological assessment based on comprehensive mechanistic understanding of cause-consequence relationships...
3.
Farcal L, Munoz Pineiro A, Riego Sintes J, Rauscher H, Rasmussen K
F1000Res
. 2024 Mar;
11:1532.
PMID: 38463031
Advanced materials are most likely to bring future economic, environmental and social benefits. At the same time, they may pose challenges regarding their safety and sustainability along the entire lifecycle....
4.
Gupta G, Cappellini F, Farcal L, Gornati R, Bernardini G, Fadeel B
Part Fibre Toxicol
. 2022 May;
19(1):33.
PMID: 35538581
Background: Copper oxide (CuO) nanoparticles (NPs) are known to trigger cytotoxicity in a variety of cell models, but the mechanism of cell death remains unknown. Here we addressed the mechanism...
5.
Creutzenberg O, Oliveira H, Farcal L, Schaudien D, Mendes A, Menezes A, et al.
Nanomaterials (Basel)
. 2022 Apr;
12(8).
PMID: 35457962
Graphene-related two-dimensional nanomaterials possess very technically promising characteristics, but gaps exist regarding their potential adverse health effects. Based on their nano-thickness and lateral micron dimensions, nanoplates exhibit particular aerodynamic properties,...
6.
Mech A, Gottardo S, Amenta V, Amodio A, Belz S, Bowadt S, et al.
Regul Toxicol Pharmacol
. 2021 Dec;
128:105093.
PMID: 34864125
The European Commission's Green Deal is a major policy initiative aiming to achieve a climate-neutral, zero-pollution, sustainable, circular and inclusive economy, driving both the New Industrial Strategy for Europe and...
7.
Oki N, Farcal L, Abdelaziz A, Florean O, Doktorova T, Exner T, et al.
Toxicol In Vitro
. 2018 Sep;
54:23-32.
PMID: 30196099
The integration of existing knowledge to support the risk assessment of chemicals is an ongoing challenge for scientists, risk assessors and risk managers. In addition, European Union regulations limiting the...
8.
Fadeel B, Farcal L, Hardy B, Vazquez-Campos S, Hristozov D, Marcomini A, et al.
Nat Nanotechnol
. 2018 Jul;
13(7):537-543.
PMID: 29980781
Engineered nanomaterials (ENMs) have tremendous potential to produce beneficial technological impact in numerous sectors in society. Safety assessment is, of course, of paramount importance. However, the myriad variations of ENM...
9.
Libalova H, Costa P, Olsson M, Farcal L, Ortelli S, Blosi M, et al.
Chemosphere
. 2018 Jan;
196:482-493.
PMID: 29324388
The rapid dissolution of copper oxide (CuO) nanoparticles (NPs) with release of ions is thought to be one of the main factors modulating their toxicity. Here we assessed the cytotoxicity...
10.
Costa P, Gosens I, Williams A, Farcal L, Pantano D, Brown D, et al.
J Appl Toxicol
. 2017 Nov;
38(3):385-397.
PMID: 29094763
Our recent studies revealed a dose-dependent proinflammatory response to copper oxide nanoparticles (CuO NPs) in rats following short-term inhalation exposure for five consecutive days. Here transcriptomics approaches were applied using...