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Lucia Valenzuela

Explore the profile of Lucia Valenzuela including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 39
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Recent Articles
1.
Vargas L, Valdivieso N, Tempio F, Simon V, Sauma D, Valenzuela L, et al.
BMC Med . 2022 Jun; 20(1):216. PMID: 35676738
Background: Chile was severely affected by COVID19 outbreaks but was also one of the first countries to start a nationwide program to vaccinate against the disease. Furthermore, Chile became one...
2.
Valenzuela L, Sepulveda S, Bahamondes P, Ramirez-Toloza G, Galanti N, Cabrera G
J Cell Biochem . 2019 May; 120(10):16733-16740. PMID: 31099049
Trypanosoma cruzi is under the attack of reactive species produced by its mammalian and insect hosts. To survive, it must repair its damaged DNA. We have shown that a base...
3.
Medina L, Castillo C, Liempi A, Herbach M, Cabrera G, Valenzuela L, et al.
Acta Trop . 2018 Jul; 186:35-40. PMID: 30018029
Congenital Chagas disease, caused by Trypanosoma cruzi (T. cruzi), has become epidemiologically relevant. The probability of congenital transmission depends on the maternal and developing fetal/newborn immune responses, placental factors and...
4.
Valenzuela L, Sepulveda S, Ponce I, Galanti N, Cabrera G
J Cell Biochem . 2018 Mar; 119(7):5985-5995. PMID: 29575156
Trypanosoma cruzi, the causative agent of Chagas' disease survives to DNA damage generated by ROS/RNS inside to their different hosts. In recent eukaryotes, oxidative DNA damage is repaired mainly by...
5.
Kunrath-Lima M, Repoles B, Alves C, Furtado C, Rajao M, Macedo A, et al.
Infect Genet Evol . 2017 Oct; 55:332-342. PMID: 28970112
Trypanosoma cruzi is a protozoan parasite and the causative agent of Chagas disease. Like most living organisms, it is susceptible to oxidative stress, and must adapt to distinct environments. Hence,...
6.
Ponce I, Aldunate C, Valenzuela L, Sepulveda S, Garrido G, Kemmerling U, et al.
J Cell Biochem . 2016 Dec; 118(7):1722-1732. PMID: 27935092
FLAP endonucleases (FEN) are involved both in DNA replication and repair by processing DNA intermediaries presenting a nucleotide flap using its phosphodiesterase activity. In spite of these important functions in...
7.
Ibarra C, Herrera V, Perez de Arce E, Gil L, Madrid A, Valenzuela L, et al.
Rev Chilena Infectol . 2016 Sep; 33(3):268-74. PMID: 27598274
Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract characterised by multi-factorial aetiology. In IBS physiopathology are involved diverse factors between them biological, psychosocial, and environmental components...
8.
Ormeno F, Barrientos C, Ramirez S, Ponce I, Valenzuela L, Sepulveda S, et al.
PLoS One . 2016 Jun; 11(6):e0157270. PMID: 27284968
Trypanosoma cruzi, the etiological agent of Chagas' disease, presents three cellular forms (trypomastigotes, epimastigotes and amastigotes), all of which are submitted to oxidative species in its hosts. However, T. cruzi...