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Lucia Motta

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Articles 10
Citations 435
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Recent Articles
1.
Motta L, Puglisi M, Pavone G, Motta G, Martorana F, Bambaci M, et al.
Cancers (Basel) . 2025 Feb; 17(3). PMID: 39941824
Background: In recent years, the role of prostate-specific membrane antigen (PSMA) in the imaging and treatment of prostate cancer (PCa) has been extensively investigated. However, despite its name, PSMA is...
2.
Pavone G, Marino A, Fisicaro V, Motta L, Spata A, Martorana F, et al.
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408687
Cervical cancer (CC) remains a prevalent malignancy and a significant global public health concern, primarily driven by persistent human papillomavirus (HPV) infections. The infectious nature of HPV underscores the preventability...
3.
Pretelli G, Mati K, Motta L, Stathis A
Explor Target Antitumor Ther . 2024 Jul; 5(3):714-741. PMID: 38966169
Antibody-drug conjugates (ADCs) have emerged as a promising class of anticancer agents. Currently, the Food and Drug Administration has granted approval to 12 compounds, with 2 later undergoing withdrawal. Moreover,...
4.
Marino A, Pavone G, Martorana F, Fisicaro V, Motta L, Spampinato S, et al.
Int J Mol Sci . 2024 Mar; 25(6). PMID: 38542195
Despite significant advances in the management of antiretroviral therapy (ART), leading to improved life expectancy for people living with HIV (PLWH), the incidence of non-AIDS-defining cancers, including breast cancer, has...
5.
Pavone G, Romano C, Martorana F, Motta L, Salvatorelli L, Zanghi A, et al.
Diagnostics (Basel) . 2022 Sep; 12(9). PMID: 36140560
Paratesticular liposarcomas are extremely rare malignant tumors originating from fat tissues, with an often-challenging diagnosis. We present here the case of a 76-year-old man with a giant paratesticular liposarcoma, initially...
6.
Massimino M, Stella S, Micale G, Motta L, Pavone G, Broggi G, et al.
Cancer Genomics Proteomics . 2022 Apr; 19(3):350-361. PMID: 35430568
Background/aim: Malignant melanoma is a skin cancer originating from the oncogenic transformation of melanocytes located in the epidermal layers. Usually, the patient's prognosis depends on timing of disease detection and...
7.
Pavone G, Motta L, Martorana F, Motta G, Vigneri P
Molecules . 2021 Dec; 26(23). PMID: 34885875
Human trophoblast cell-surface antigen-2 (Trop-2) is a membrane glycoprotein involved in cell proliferation and motility, frequently overexpressed in epithelial tumors. Thus, it represents an attractive target for anticancer therapies. Sacituzumab...
8.
Martorana F, Motta G, Pavone G, Motta L, Stella S, Vitale S, et al.
Front Pharmacol . 2021 May; 12:662232. PMID: 33995085
The serine/threonine kinase AKT is a key component of the PI3K/AKT/mTOR signaling pathway as it exerts a pivotal role in cell growth, proliferation, survival, and metabolism. Deregulation of this pathway...
9.
Martorana F, Lanzafame K, Pavone G, Motta L, Motta G, Inzerilli N, et al.
Case Rep Oncol Med . 2021 Mar; 2021:6692538. PMID: 33728080
Intestinal and pancreatic metastases are rare and often challenging to recognize and manage. Lung cancer patients with enteric involvement usually display poor outcomes. Hyperprogression to immunotherapy represents a concern, even...
10.
Casale P, Saita A, Lazzeri M, Lughezzani G, Hurle R, Fasulo V, et al.
Minerva Urol Nefrol . 2019 Feb; 71(3):273-279. PMID: 30700081
Background: There is an unmet clinical need for more biochemical specific tests that may detect clinically significant recurrent PCa at an early stage after radical prostatectomy (RP). Our purpose is...