Lucia Leonardi
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Explore the profile of Lucia Leonardi including associated specialties, affiliations and a list of published articles.
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47
Citations
278
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Recent Articles
1.
Paparella R, Panvino F, Leonardi L, Pucarelli I, Menghi M, Micangeli G, et al.
Pharmaceutics
. 2025 Jan;
17(1).
PMID: 39861765
Background/objectives: Water-soluble vitamins, comprising the B-complex vitamins and vitamin C, are essential for normal growth, cellular metabolism, and immune function in pediatric populations. Due to limited storage in the body,...
2.
Leonardi L, Perna C, Bernabei I, Fiore M, Ma M, Frankovich J, et al.
Children (Basel)
. 2024 Sep;
11(9).
PMID: 39334578
Pediatric acute-onset neuropsychiatric syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), represent an overlapping group of disorders which is characterized by acute-onset obsessive compulsive disorders, eating...
3.
Rossini L, Ricci S, Montin D, Azzari C, Gambineri E, Tellini M, et al.
J Clin Immunol
. 2024 Apr;
44(5):105.
PMID: 38676773
Kabuki Syndrome (KS) is a multisystemic genetic disorder. A portion of patients has immunological manifestations characterized by increased susceptibility to infections and autoimmunity. Aiming to describe the clinical and laboratory...
4.
Federici S, Cinicola B, La Torre F, Castagnoli R, Lougaris V, Giardino G, et al.
Front Pediatr
. 2024 Feb;
11:1258301.
PMID: 38357265
Systemic autoinflammatory diseases (SAIDs) are disorders of innate immunity, which are characterized by unprovoked recurrent flares of systemic inflammation often characterized by fever associated with clinical manifestations mainly involving the...
5.
Migliavacca M, Barzaghi F, Fossati C, Rancoita P, Gabaldo M, Dionisio F, et al.
Nat Med
. 2024 Feb;
30(2):488-497.
PMID: 38355973
Adenosine deaminase (ADA) deficiency leads to severe combined immunodeficiency (SCID). Previous clinical trials showed that autologous CD34 cell gene therapy (GT) following busulfan reduced-intensity conditioning is a promising therapeutic approach...
6.
Leonardi L, Lorenzetti G, Carsetti R, Piano Mortari E, Guido C, Zicari A, et al.
Front Pediatr
. 2024 Jan;
11:1216282.
PMID: 38239595
This cross-sectional study aimed to contribute to the definition of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) pathophysiology. An extensive immunological assessment has been conducted to investigate both...
7.
Conti F, Moratti M, Leonardi L, Catelli A, Bortolamedi E, Filice E, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830631
Background: The large-scale utilization of immunoglobulins in patients with inborn errors of immunity (IEIs) since 1952 prompted the discovery of their key role at high doses as immunomodulatory and anti-inflammatory...
8.
Fratini E, Migliavacca M, Barzaghi F, Fossati C, Giannelli S, Monti I, et al.
Front Immunol
. 2023 Jul;
14:1187959.
PMID: 37435083
Hemophagocytic inflammatory syndrome (HIS) is a rare form of secondary hemophagocytic lymphohistiocytosis caused by an impaired equilibrium between natural killer and cytotoxic T-cell activity, evolving in hypercytokinemia and multiorgan failure....
9.
Leonardi L, Testa A, Feleppa M, Paparella R, Conti F, Marzollo A, et al.
Front Pediatr
. 2023 Jun;
11:1087002.
PMID: 37360370
Kabuki syndrome (KS) is a rare multisystemic disease due to mutations in the or genes, which act as epigenetic modulators of different processes, including immune response. The syndrome is characterized...
10.
Balduit A, Bianco A, Mangogna A, Zicari A, Leonardi L, Cinicola B, et al.
Front Immunol
. 2023 Jun;
14:1192690.
PMID: 37304269
Primary complement system (C) deficiencies are rare but notably associated with an increased risk of infections, autoimmunity, or immune disorders. Patients with terminal pathway C-deficiency have a 1,000- to 10,000-fold-higher...