Lucia De Franceschi
Overview
Explore the profile of Lucia De Franceschi including associated specialties, affiliations and a list of published articles.
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Articles
177
Citations
4042
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Recent Articles
1.
Siciliano A, DAlessandro A, Matte A, Bisello G, Bertoldi M, Dzieciatkowska M, et al.
Blood Adv
. 2025 Mar;
PMID: 40085946
beta-thalassemia (beta-thal) is a worldwide hereditary red cell disorder characterized by severe chronic anemia. Recently, the pyruvate kinase (PK) activator mitapivat has been shown to improve anemia and ineffective erythropoiesis...
2.
De Franceschi L, Locatelli F, Rees D, Chabannon C, Dalle J, Rivella S, et al.
Hemasphere
. 2025 Mar;
9(3):e70089.
PMID: 40084235
Sickle cell disease (SCD) remains associated with reduced life expectancy and poor quality of life despite improvements observed in the last decades mostly related to comprehensive care, use of hydroxycarbamide,...
3.
Pinto V, Cima R, Di Maggio R, Alga M, Gigante A, Longo F, et al.
J Clin Med
. 2025 Feb;
14(3).
PMID: 39941620
Hereditary hemoglobin disorders are the most common globally distributed monogenic red cell diseases. The rights of women with thalassemia or sickle cell disease (SCD) to motherhood need to be protected...
4.
17(R)-RESOLVIN D1 PROTECTS AGAINST SICKLE CELL-RELATED INFLAMMATORY CARDIOMYOPATHY IN HUMANIZED MICE
Federti E, Mattoscio D, Recchiuti A, Matte A, Monti M, Cozzolino F, et al.
Blood
. 2025 Feb;
PMID: 39928855
Cardiovascular disease has been recognized as the main cause of death in adults with sickle cell disease (SCD). Although the exact mechanism linking SCD to cardiomyopathy remains elusive, a possible...
5.
Gianesin B, Piel F, Musallam K, Barella S, Casale M, Cassinerio E, et al.
Haematologica
. 2025 Jan;
PMID: 39844751
Not available.
6.
Bou-Fakhredin R, Cappellini M, Taher A, De Franceschi L
Am J Hematol
. 2024 Oct;
100(1):103-115.
PMID: 39400943
Beta (β)-thalassemia and sickle cell disease (SCD) are characterized by a hypercoagulable state, which can significantly influence organ complication and disease severity. While red blood cells (RBCs) and erythroblasts continue...
7.
Caminati M, Carpagnano L, Alberti C, Amaddeo F, Bixio R, Caldart F, et al.
World Allergy Organ J
. 2024 Aug;
17(8):100928.
PMID: 39156600
Hypereosinophilic syndromes (HES) represent a group of rare dis-immune conditions characterized by blood hyper-eosinophilia and eosinophilic related burden. Especially the idiopathic subtype (I-HES) is particularly difficult to diagnose because of...
8.
Iolascon A, Andolfo I, Russo R, Sanchez M, Busti F, Swinkels D, et al.
Hemasphere
. 2024 Jul;
8(7):e108.
PMID: 39011129
Iron is an essential nutrient and a constituent of ferroproteins and enzymes crucial for human life. Generally, nonmenstruating individuals preserve iron very efficiently, losing less than 0.1% of their body...
9.
Pinto V, Mazzi F, De Franceschi L
Blood
. 2024 May;
144(8):853-866.
PMID: 38820588
In this last decade, a deeper understanding of the pathophysiology of hereditary red cell disorders and the development of novel classes of pharmacologic agents have provided novel therapeutic approaches to...
10.
Mbiandjeu S, Siciliano A, Matte A, Federti E, Perduca M, Melisi D, et al.
Antioxidants (Basel)
. 2024 Apr;
13(4).
PMID: 38671902
Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here,...