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Lucia Alvarez-Gonzalez

Explore the profile of Lucia Alvarez-Gonzalez including associated specialties, affiliations and a list of published articles. Areas
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Citations 110
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Recent Articles
1.
Liang X, Arrey G, Qin Y, Alvarez-Gonzalez L, Hariprakash J, Ma J, et al.
Nat Commun . 2025 Feb; 16(1):1872. PMID: 39984484
eccDNA is a driver of many cancers and a potential intermediate in other age-related disorders. However, little is known about the mechanisms underlying eccDNA formation in healthy tissue and how...
2.
Coulee M, de la Iglesia A, Blanco M, Gobe C, Lapoujade C, Ialy-Radio C, et al.
Commun Biol . 2025 Jan; 8(1):138. PMID: 39875559
The H3K79 methyltransferase DOT1L is essential for multiple aspects of mammalian development where it has been shown to regulate gene expression. Here, by producing and integrating epigenomic and spike-in RNA-seq...
3.
Pujol G, Marin-Gual L, Gonzalez-Rodelas L, Alvarez-Gonzalez L, Chauvigne F, Cerda J, et al.
J Hazard Mater . 2024 Nov; 481():136529. PMID: 39556913
Nanoplastics pollution is a rising environmental concern whose impacts on biodiversity and human health are far from being understood. This is particularly salient in aquatic ecosystems, where the majority of...
4.
Alvarez-Gonzalez L, Ruiz-Herrera A
Annu Rev Anim Biosci . 2024 Nov; 13(1):49-71. PMID: 39531399
Studies examining the evolution of genomes have focused mainly on sequence conservation. However, the inner working of a cell implies tightly regulated crosstalk between complex gene networks controlled by small...
5.
Bista B, Gonzalez-Rodelas L, Alvarez-Gonzalez L, Wu Z, Montiel E, Lee L, et al.
Genome Res . 2024 Oct; 34(10):1553-1569. PMID: 39414368
Understanding the evolution of chromatin conformation among species is fundamental to elucidate the architecture and plasticity of genomes. Nonrandom interactions of linearly distant loci regulate gene function in species-specific patterns,...
6.
Massafret O, Barragan M, Alvarez-Gonzalez L, Aran B, Martin-Mur B, Esteve-Codina A, et al.
Cells Dev . 2024 Jun; 179:203935. PMID: 38914137
Human embryonic stem cells (hESCs) derived from blastocyst stage embryos present a primed state of pluripotency, whereas mouse ESCs (mESCs) display naïve pluripotency. Their unique characteristics make naïve hESCs more...
7.
Marin-Garcia C, Alvarez-Gonzalez L, Marin-Gual L, Casillas S, Picon J, Yam K, et al.
Mol Biol Evol . 2024 Mar; 41(4). PMID: 38513632
Chromosomal fusions represent one of the most common types of chromosomal rearrangements found in nature. Yet, their role in shaping the genomic landscape of recombination and hence genome evolution remains...
8.
Alonso-Alonso S, Esteve-Codina A, Martin-Mur B, Alvarez-Gonzalez L, Ruiz-Herrera A, Santalo J, et al.
Front Cell Dev Biol . 2023 Oct; 11:1274660. PMID: 37876553
Embryonic stem cell (ESC) derivation from single blastomeres of 8-cell mouse embryos results in lower derivation rates than that from whole blastocysts, raising a biological question about the developmental potential...
9.
Alvarez-Gonzalez L, Arias-Sarda C, Montes-Espuna L, Marin-Gual L, Vara C, Lister N, et al.
Cell Rep . 2022 Dec; 41(12):111839. PMID: 36543130
Studying the similarities and differences in genomic interactions between species provides fertile grounds for determining the evolutionary dynamics underpinning genome function and speciation. Here, we describe the principles of 3D...
10.
Alvarez-Gonzalez L, Burden F, Doddamani D, Malinverni R, Leach E, Marin-Garcia C, et al.
Nat Commun . 2022 May; 13(1):2608. PMID: 35546158
Chromosome folding has profound impacts on gene regulation, whose evolutionary consequences are far from being understood. Here we explore the relationship between 3D chromatin remodelling in mouse germ cells and...