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Lucas Taoro-Gonzalez

Explore the profile of Lucas Taoro-Gonzalez including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 598
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Recent Articles
1.
Taoro-Gonzalez L, Pereda D, Valdes-Baizabal C, Gonzalez-Gomez M, Perez J, Mesa-Herrera F, et al.
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806435
Long-chain polyunsaturated fatty acids (LCPUFA), essential molecules whose precursors must be dietary supplied, are highly represented in the brain contributing to numerous neuronal processes. Recent findings have demonstrated that LCPUFA...
2.
Sancho-Alonso M, Taoro-Gonzalez L, Cabrera-Pastor A, Felipo V, Teruel-Marti V
Neurochem Res . 2022 Apr; 47(7):2016-2031. PMID: 35386048
Chronic hyperammonemia alters membrane expression of AMPA and NMDA receptors subunits in hippocampus leading to impaired memory and learning. Increasing extracellular cGMP normalizes these alterations. However, it has not been...
3.
Taoro-Gonzalez L, Cabrera-Pastor A, Sancho-Alonso M, Felipo V
Vitam Horm . 2022 Feb; 118:247-288. PMID: 35180929
Cyclic Guanosine-Monophosphate (cGMP) is implicated as second messenger in a plethora of pathways and its effects are executed mainly by cGMP-dependent protein kinases (PKG). It is involved in both peripheral...
4.
Mesa-Herrera F, Taoro-Gonzalez L, Valdes-Baizabal C, Diaz M, Marin R
Int J Mol Sci . 2019 Aug; 20(15). PMID: 31382686
Lipids in the brain are major components playing structural functions as well as physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic transmission, signal transduction, membrane compartmentalization, and...
5.
Taoro-Gonzalez L, Cabrera-Pastor A, Sancho-Alonso M, Arenas Y, Meseguer-Estornell F, Balzano T, et al.
FASEB J . 2019 Jun; 33(9):9913-9928. PMID: 31162953
Activated microglia and increased brain IL-1β play a main role in cognitive impairment in much pathology. We studied the role of IL-1β in neuroinflammation-induced impairment of the following different types...
6.
Cabrera-Pastor A, Llansola M, Montoliu C, Malaguarnera M, Balzano T, Taoro-Gonzalez L, et al.
Acta Physiol (Oxf) . 2019 Mar; 226(2):e13270. PMID: 30830722
Several million patients with liver cirrhosis suffer minimal hepatic encephalopathy (MHE), with mild cognitive and coordination impairments that reduce their quality of life and life span. Hyperammonaemia and peripheral inflammation...
7.
Balzano T, Dadsetan S, Forteza J, Cabrera-Pastor A, Taoro-Gonzalez L, Malaguarnera M, et al.
J Hepatol . 2019 Jan; 73(3):582-592. PMID: 30654069
Background & Aims: Chronic hyperammonemia induces neuroinflammation which mediates cognitive impairment. How hyperammonemia induces neuroinflammation remains unclear. We aimed to assess whether: chronic hyperammonemia induces peripheral inflammation, and whether this...
8.
Cabrera-Pastor A, Arenas Y, Taoro-Gonzalez L, Montoliu C, Felipo V
Neuropharmacology . 2019 Jan; 161:107496. PMID: 30641078
Trafficking of glutamate, glutamine and GABA between astrocytes and neurons is essential to maintain proper neurotransmission. Chronic hyperammonemia alters neurotransmission and cognitive function. The aims of this work were to...
9.
Taoro-Gonzalez L, Arenas Y, Cabrera-Pastor A, Felipo V
Mol Neurobiol . 2018 Oct; 56(6):4428-4439. PMID: 30328550
Chronic hyperammonemia impairs spatial memory by altering membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus. Intracerebral administration of extracellular cGMP to hyperammonemic rats restores spatial memory...
10.
Taoro-Gonzalez L, Arenas Y, Cabrera-Pastor A, Felipo V
J Neuroinflammation . 2018 Feb; 15(1):36. PMID: 29422059
Background: Hyperammonemic rats reproduce the cognitive alterations of patients with hepatic encephalopathy, including altered spatial memory, attributed to altered membrane expression of AMPA receptor subunits in hippocampus. Neuroinflammation mediates these...