Lucas Resende Dutra Sousa
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Explore the profile of Lucas Resende Dutra Sousa including associated specialties, affiliations and a list of published articles.
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8
Citations
15
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Recent Articles
1.
Amparo T, Almeida T, Sousa L, Xavier V, Silva G, Brandao G, et al.
Pharmaceutics
. 2025 Feb;
17(2).
PMID: 40006574
Cancer represents a significant societal, public health, and economic challenge. Conventional chemotherapy is based on systemic administration; however, it has current limitations, including poor bioavailability, high-dose requirements, adverse side effects,...
2.
Sousa L, Duarte T, Xavier V, das Merces A, Vieira G, Martins M, et al.
Pharmaceutics
. 2024 Jun;
16(6).
PMID: 38931921
Chagas disease (CD) is a worldwide public health problem. Benznidazole (BZ) is the drug used to treat it. However, in its commercial formulation, it has significant side effects and is...
3.
Amparo T, Sousa L, Xavier V, Seibert J, Paiva D, da Silva D, et al.
Pharmaceutics
. 2024 Jun;
16(6).
PMID: 38931824
The treatment of skin and soft tissue infections (SSTIs) can be challenging due to bacterial resistance, particularly from strains like MRSA and biofilm formation. However, combining conventional antibiotics with natural...
4.
Sousa L, Santos M, Sampaio L, Faustino C, Guigueno M, Freitas K, et al.
Pharmaceuticals (Basel)
. 2024 Jun;
17(6).
PMID: 38931388
Melanoma, primarily caused by solar ultraviolet (UV) radiation, can be prevented by the use of sunscreens. However, the use of synthetic sunscreens raises environmental concerns. Natural compounds with antioxidant photoprotective...
5.
Valverde T, Dos Santos V, Viana P, Costa G, de Goes A, Sousa L, et al.
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38673856
Immune response to biomaterials, which is intimately related to their surface properties, can produce chronic inflammation and fibrosis, leading to implant failure. This study investigated the development of magnetic nanoparticles...
6.
Sousa L, Amparo T, Souza G, Ferraz A, Fonseca K, Azevedo A, et al.
Molecules
. 2023 Dec;
28(23).
PMID: 38067542
Chagas disease (CD) is a worldwide public health problem, and the drugs available for its treatment have severe limitations. Red propolis is a natural extract known for its high content...
7.
Valverde T, Soares B, Nascimento A, Andrade A, Sousa L, Vieira P, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982196
Many activities have been described for propolis, including, antiviral, antibacterial, antifungal, anti-inflammatory, immunoregulatory, antioxidant and wound healing properties. Recently, propolis has been highlighted due to its potential application in the...
8.
Reynaldo J, Novack K, Sousa L, Vieira P, Amparo T, Souza G, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142698
Modified release systems depend on the selection of an appropriate agent capable of controlling the release of the drug, sustaining the therapeutic action over time, and/or releasing the drug at...
9.
Cunha E, Torchelsen F, Fonseca K, Sousa L, Vieira P, Carneiro C, et al.
Exp Parasitol
. 2022 May;
238:108266.
PMID: 35490799
Treatment for Chagas disease has limited efficacy in the chronic phase. We evaluated benznidazole (BZ) and itraconazole (ITZ) individually and in association in dogs 16 months after infection with a...