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Lucas Deseins

Explore the profile of Lucas Deseins including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Billiet L, Jansen H, Pille M, Boehme L, Sanchez Sanchez G, De Cock L, et al.
Eur J Immunol . 2024 Sep; 54(12):e2451265. PMID: 39246170
In vitro cultures remain crucial for studying the fundamental mechanisms of human T-cell development. Here, we introduce a novel in vitro cultivation system based on ThymoSpheres (TS): dense spheroids consisting...
2.
De Munter S, Buhl J, De Cock L, Van Parys A, Daneels W, Pascal E, et al.
Cancer Immunol Res . 2024 Jun; 12(9):1236-1251. PMID: 38874582
CD70 is an attractive target for chimeric antigen receptor (CAR) T-cell therapy for the treatment of both solid and liquid malignancies. However, the functionality of CD70-specific CAR T cells is...
3.
Ingels J, De Cock L, Stevens D, Mayer R, Thery F, Sanchez Sanchez G, et al.
Cell Rep Med . 2024 Apr; 5(5):101516. PMID: 38626769
Non-small cell lung cancer (NSCLC) is known for high relapse rates despite resection in early stages. Here, we present the results of a phase I clinical trial in which a...
4.
Pille M, Avila J, Sanchez Sanchez G, Goetgeluk G, De Munter S, Jansen H, et al.
Front Immunol . 2023 Jun; 14:1188099. PMID: 37350958
The Wiskott-Aldrich syndrome (WAS) is an X-linked primary immune deficiency caused by a mutation in the WAS gene. This leads to altered or absent WAS protein (WASp) expression and function...