Alpha 2.0
Login Register
» Authors » Lucas Antonio Duarte Nicolau

Lucas Antonio Duarte Nicolau

Explore the profile of Lucas Antonio Duarte Nicolau including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 23
Citations 104
Followers 0
Related Specialties
Pharmacology
Biomedical Engineering
Toxicology
Top 10 Co-Authors
Jand Venes Rolim Medeiros
Afonso Caricati-Neto
Fernando Sabia Tallo
Francisco Sandro Menezes-Rodrigues
Jand-Venes Rolim Medeiros
Murched Omar Taha
Marcellus Henrique Loiola Ponte Souza
Marcelo Pires-Oliveira
Thiago Meneses Araujo Leite Sales
Erisvaldo Amarante de Araujo
Published In
Biomedicines
J Cardiovasc Dev Dis
Acta Cir Bras
Mar Drugs
Phytomedicine
Affiliations
Soon will be listed here.
Recent Articles
1.
Mucosal integrity of the larynx and hypopharynx and the response to proton pump inhibitors in patients with laryngopharyngeal reflux
Pompeu C, Sales T, Nicolau L, de Souza Matos A, Borsaro A, Coutinho T, et al.
Eur Arch Otorhinolaryngol . 2025 Feb; PMID: 39891692
Purpose: To evaluate whether impairment of integrity of laryngeal and hypopharyngeal mucosa in laryngopharyngeal reflux (LPR) could be related to response to proton pump inhibitors (PPIs). Methods: Chronic hoarseness with...
2.
Cardiotoxic and Cardioprotective Effects of Methylene Blue in the Animal Model of Cardiac Ischemia and Reperfusion
Fernandes Junior H, de Araujo E, Machado Junior J, Lutz Motta F, Guarize G, Cheng L, et al.
Biomedicines . 2024 Nov; 12(11). PMID: 39595141
Treatment of patients with myocardial ischemic diseases crucially involves cardiac reperfusion (CR). However, oxidative stress and tissue lesions caused by CR may also lead to lethal complications, such as arrythmias...
3.
Use of etomidate in endotracheal intubations in the emergency room during the COVID-19 pandemic: a randomized clinical trial
Tallo F, Pires-Oliveira M, Nakai M, Nicolau L, Medeiros J, Gehrke F, et al.
Acta Cir Bras . 2024 Sep; 39:e395724. PMID: 39258618
Purpose: Shock, cardiovascular problems, and respiratory failure constitute the main causes of death in patients cared in medical emergency rooms. Patients commonly require orotracheal intubation (OTI), a fact that has...
4.
Comprehensive analysis of gastrointestinal side effects in COVID-19 patients undergoing combined pharmacological treatment with azithromycin and hydroxychloroquine: a systematic review and network meta-analysis
Pacheco G, Lopes A, Oliveira A, Correa W, Lima L, de Souza M, et al.
Crit Rev Toxicol . 2024 Jun; 54(6):345-358. PMID: 38860720
During the COVID-19 pandemic, several drugs were repositioned and combined to quickly find a way to mitigate the effects of the infection. However, the adverse effects of these combinations on...
5.
Exploring the clinical relevance of "Angico Gum": an effective biopolymer for topical protection of oesophageal mucosa in gastroesophageal reflux disease patients
Bingana R, Nicolau L, Sales T, Paula S, do Carmo Neto J, Castro I, et al.
J Pharm Pharmacol . 2024 Mar; 76(6):732-742. PMID: 38546507
Objectives: Angico gum (AG) (Anadenanthera colubrina var. Cebil [Griseb.] Altschul) is utilized by some Brazilian communities to alleviate symptoms from gastroesophageal reflux disease. Here, we aimed to investigate the "in...
6.
Cardiotoxic Effects Produced by Omeprazole and Methylene Blue in an Animal Model of Cardiac Ischemia and Reperfusion and Potential Implications for the Pharmacological Strategy for Vasoplegic Syndrome
de Araujo E, Tallo F, Oliveira A, Toghlobi G, Arantes R, Balsimelli R, et al.
Biomedicines . 2024 Mar; 12(3). PMID: 38540195
Defined as systemic hypotension caused by intense vasodilation due to the loss of systemic vascular resistance, vasoplegic syndrome (VS) is associated with elevated morbidity and mortality in humans. Although vasopressors...
7.
Long-term administration of omeprazole in mice: a study of behavior, inflammatory, and oxidative stress alterations with focus on central nervous system
Coelho D, Costa Junior D, da Silva D, Alves A, Chaves R, Reboucas M, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2024 Mar; 397(8):6165-6175. PMID: 38433146
Chronic use of omeprazole has been linked to central effects alongside with the global concern of increasing appearance of neuropsychiatric disorders. This study aimed to identifying behavioral, inflammatory, and oxidative...
8.
Pharmacological Modulation of the Ca/cAMP/Adenosine Signaling in Cardiac Cells as a New Cardioprotective Strategy to Reduce Severe Arrhythmias in Myocardial Infarction
Tallo F, de Santana P, Pinto S, Lima R, de Araujo E, Tavares J, et al.
Pharmaceuticals (Basel) . 2023 Oct; 16(10). PMID: 37895945
Acute myocardial infarction (AMI) is the main cause of morbidity and mortality worldwide and is characterized by severe and fatal arrhythmias induced by cardiac ischemia/reperfusion (CIR). However, the molecular mechanisms...
9.
Protective effect of alpha-ketoglutarate against water-immersion restraint stress-induced gastric mucosal damage in mice
Lopes A, Araujo A, Chaves L, Pacheco G, Oliveira A, Silva K, et al.
Eur J Pharmacol . 2023 Oct; 960:176118. PMID: 37871764
Gastric lesions have several aetiologies, among which stress is the most prominent. Therefore, identification of new therapies to prevent stress is of considerable importance. Alpha-ketoglutarate (α-kg) several beneficial effects and...
10.
Pharmacological Modulation by Low Molecular Weight Heparin of Purinergic Signaling in Cardiac Cells Prevents Arrhythmia and Lethality Induced by Myocardial Infarction
Braga Filho C, Barbosa A, Nicolau L, Medeiros J, Pires-Oliveira M, Povoa R, et al.
J Cardiovasc Dev Dis . 2023 Mar; 10(3). PMID: 36975867
Background: Although several studies suggest that heparins prevent arrhythmias caused by acute myocardial infarction (AMI), the molecular mechanisms involved remain unclear. To investigate the involvement of pharmacological modulation of adenosine...