Luca Peruzzotti-Jametti
Overview
Explore the profile of Luca Peruzzotti-Jametti including associated specialties, affiliations and a list of published articles.
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61
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1411
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Recent Articles
31.
Willis C, Nicaise A, Peruzzotti-Jametti L, Pluchino S
Brain Res
. 2019 Dec;
1729:146615.
PMID: 31863730
Compelling evidence from experimental animal disease models and early-phase clinical trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path towards the development of clinically applicable exogenous...
32.
Bernstock J, Peruzzotti-Jametti L, Leonardi T, Vicario N, Ye D, Lee Y, et al.
EBioMedicine
. 2019 Mar;
42:214-224.
PMID: 30905846
Background: Neural stem cell (NSC)-based therapies hold great promise for treating diseases of the central nervous system (CNS). However, several fundamental problems still need to be overcome to fully exploit...
33.
Falcone C, Santo M, Liuzzi G, Cannizzaro N, Grudina C, Valencic E, et al.
Cereb Cortex
. 2019 Mar;
29(12):4903-4918.
PMID: 30821834
Neocortical astrogenesis follows neuronogenesis and precedes oligogenesis. Among key factors dictating its temporal articulation, there are progression rates of pallial stem cells (SCs) towards astroglial lineages as well as activation...
34.
Peruzzotti-Jametti L, Pluchino S
Trends Mol Med
. 2018 Aug;
24(10):838-855.
PMID: 30100517
The lack of effective treatment options for chronic neurological conditions, such as multiple sclerosis (MS), highlights the need to re-evaluate disease pathophysiology in the process of identifying novel therapeutic targets....
35.
LEpiscopo F, Tirolo C, Peruzzotti-Jametti L, Serapide M, Testa N, Caniglia S, et al.
Stem Cells
. 2018 Mar;
36(8):1179-1197.
PMID: 29575325
During aging-one the most potent risk factors for Parkinson's disease (PD)-both astrocytes and microglia undergo functional changes that ultimately hamper homoeostasis, defense, and repair of substantia nigra pars compacta (SNpc)...
36.
Smith J, Braga A, Verheyen J, Basilico S, Bandiera S, Alfaro-Cervello C, et al.
Mol Ther Nucleic Acids
. 2018 Mar;
10:103-121.
PMID: 29499926
In response to injuries to the CNS, astrocytes enter a reactive state known as astrogliosis, which is believed to be deleterious in some contexts. Activated astrocytes overexpress intermediate filaments including...
37.
Peruzzotti-Jametti L, Bernstock J, Vicario N, Costa A, Kwok C, Leonardi T, et al.
Cell Stem Cell
. 2018 Feb;
22(3):355-368.e13.
PMID: 29478844
Neural stem cell (NSC) transplantation can influence immune responses and suppress inflammation in the CNS. Metabolites, such as succinate, modulate the phenotype and function of immune cells, but whether and...
38.
Mauri E, Sacchetti A, Vicario N, Peruzzotti-Jametti L, Rossi F, Pluchino S
Biomater Sci
. 2018 Jan;
6(3):501-510.
PMID: 29368775
The use of neural stem cells (NSCs) in cell therapy has become a powerful tool used for the treatment of central nervous system diseases, including traumatic brain and spinal cord...
39.
Bernstock J, Ye D, Gessler F, Lee Y, Peruzzotti-Jametti L, Baumgarten P, et al.
Sci Rep
. 2017 Aug;
7(1):7425.
PMID: 28785061
Protein SUMOylation is a dynamic post-translational modification shown to be involved in a diverse set of physiologic processes throughout the cell. SUMOylation has also been shown to play a role...
40.
Iraci N, Gaude E, Leonardi T, Costa A, Cossetti C, Peruzzotti-Jametti L, et al.
Nat Chem Biol
. 2017 Jul;
13(9):951-955.
PMID: 28671681
Extracellular vesicles (EVs) are membrane particles involved in the exchange of a broad range of bioactive molecules between cells and the microenvironment. Although it has been shown that cells can...