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Luc Van Gaal

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Articles 145
Citations 5591
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Recent Articles
1.
Van Dijck E, Diels S, Fransen E, Cremers T, Verrijken A, Dirinck E, et al.
Antioxidants (Basel) . 2024 Sep; 13(9). PMID: 39334710
The paraoxonase () gene family (including PON1, PON2, and PON3), is known for its anti-oxidative and anti-inflammatory properties, protecting against metabolic diseases such as obesity and metabolic dysfunction-associated steatotic liver...
2.
Van Dessel K, Verrijken A, De Block C, Verhaegen A, Peiffer F, Van Gaal L, et al.
Clin Nutr ESPEN . 2024 Jan; 59:422-435. PMID: 38220405
Background & Aims: Weight reduction programs in people with overweight or obesity can be informed by indirect calorimetry (IC) which is the gold standard to measure basal metabolic rate (BMR)....
3.
Ibrahim M, Ba-Essa E, Baker J, Cahn A, Ceriello A, Cosentino F, et al.
Diabetes Metab Res Rev . 2023 Dec; 40(3):e3755. PMID: 38115715
In the primary care setting providers have more tools available than ever before to impact positively obesity, diabetes, and their complications, such as renal and cardiac diseases. It is important...
4.
Clavreul L, Bernard L, Cotte A, Hennuyer N, Bourouh C, Devos C, et al.
Metabolism . 2023 Nov; 151:155720. PMID: 37926201
Background And Aims: Peroxisome Proliferator-Activated Receptor α (PPARα) is a key regulator of hepatic lipid metabolism and therefore a promising therapeutic target against Metabolic-dysfunction Associated Steatotic Liver Diseases (MASLD). However,...
5.
Lalloyer F, Mogilenko D, Verrijken A, Haas J, Lamaziere A, Kouach M, et al.
J Hepatol . 2023 May; 79(4):898-909. PMID: 37230231
Background & Aims: Roux-en-Y gastric bypass (RYGB), the most effective surgical procedure for weight loss, decreases obesity and ameliorates comorbidities, such as non-alcoholic fatty liver (NAFLD) and cardiovascular (CVD) diseases....
6.
De Herdt C, De Block C, Francque S, Verrijken A, Van Dessel K, Van Gaal L, et al.
Endocrine . 2023 Mar; 80(1):54-63. PMID: 36857008
Purpose: To study the association between testosterone and non-alcoholic fatty liver disease (NAFLD) since prior studies have reported inconsistent results. Methods: A retrospective analysis was performed including obese men who...
7.
Van Dijck E, Beckers S, Diels S, Huybrechts T, Verrijken A, Van Hoorenbeeck K, et al.
Genes (Basel) . 2022 Oct; 13(10). PMID: 36292633
Recently, it was reported that heterozygous PCSK1 variants, causing partial PC1/3 deficiency, result in a significant increased risk for obesity. This effect was almost exclusively generated by the rare p.Y181H...
8.
Zanoni P, Panteloglou G, Othman A, Haas J, Meier R, Rimbert A, et al.
Circ Res . 2021 Nov; 130(1):80-95. PMID: 34809444
Background: The LDLR (low-density lipoprotein receptor) in the liver is the major determinant of LDL-cholesterol levels in human plasma. The discovery of genes that regulate the activity of LDLR helps...
9.
Hens W, Vissers D, Verhaeghe N, Gielen J, Van Gaal L, Taeymans J
Int J Environ Res Public Health . 2021 Aug; 18(15). PMID: 34360293
Ectopic fat leads to metabolic health problems. This research aimed to assess the effectiveness of a hypocaloric diet intervention together with an unsupervised exercise training program in comparison with a...
10.
Nachit M, Kwanten W, Thissen J, Op de Beeck B, Van Gaal L, Vonghia L, et al.
J Hepatol . 2021 Apr; 75(2):292-301. PMID: 33865909
Background & Aims: Studies exploring the relationship between muscle fat content and non-alcoholic fatty liver disease (NAFLD) are scarce. Herein, we aimed to evaluate the association of muscle mass and...