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Luc Kestens

Explore the profile of Luc Kestens including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 96
Citations 2194
Followers 0
Related Specialties
Infectious Diseases
General Medicine
Science
Top 10 Co-Authors
Wim Jennes
Robert Colebunders
Souleymane Mboup
William Worodria
Makhtar Camara
Harriet Mayanja-Kizza
Chris Vereecken
Katrien Fransen
Geraldine Daneau
Marguerite Massinga-Loembe
Published In
PLoS One
J Acquir Immune Defic Syndr
J Infect Dis
Cytometry B Clin Cytom
AIDS Res Hum Retroviruses
Affiliations
Soon will be listed here.
Recent Articles
1.
Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1
Chissumba R, Magul C, Macamo R, Monteiro V, Enosse M, Macicame I, et al.
BMC Immunol . 2022 Mar; 23(1):12. PMID: 35287587
Background: Human immunodeficiency virus type 1 (HIV-1) causes impairment of T and B cell responses, which begins during the acute phase of infection and is not completely restored by antiretroviral...
2.
Genetic variation in the immune system and malaria susceptibility in infants: a nested case-control study in Nanoro, Burkina Faso
Natama H, Rovira-Vallbona E, Krit M, Guetens P, Sorgho H, Some M, et al.
Malar J . 2021 Feb; 20(1):94. PMID: 33593344
Background: Genetic polymorphisms in the human immune system modulate susceptibility to malaria. However, there is a paucity of data on the contribution of immunogenetic variants to malaria susceptibility in infants,...
3.
Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS
Goovaerts O, Massinga-Loembe M, Ondoa P, Ceulemans A, Worodria W, Mayanja-Kizza H, et al.
PLoS One . 2020 Dec; 15(12):e0244800. PMID: 33382831
Background: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in HIV-TB co-infected patients receiving antiretroviral therapy (ART) has been linked to neutrophil activation. Anti-neutrophil cytoplasmic antibodies (ANCAs) are also associated with neutrophil...
4.
Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes
Prajapati S, Borlon C, Rovira-Vallbona E, Gruszczyk J, Menant S, Tham W, et al.
Sci Rep . 2019 Jun; 9(1):8943. PMID: 31221984
Plasmodium vivax parasites preferentially invade reticulocyte cells in a multistep process that is still poorly understood. In this study, we used ex vivo invasion assays and population genetic analyses to...
5.
Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS
Goovaerts O, Massinga-Loembe M, Ondoa P, Ceulemans A, Worodria W, Mayanja-Kizza H, et al.
PLoS One . 2019 Apr; 14(4):e0215991. PMID: 31022273
Background: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral therapy (ART). The exact contribution of T cells, natural killer (NK) cells, and...
6.
CD4-T cell enumeration in human immunodeficiency virus (HIV)-infected patients: A laboratory performance evaluation of Muse Auto CD4/CD4% system by World Health Organization prequalification of in vitro diagnostics
Ceulemans A, Bouzahzah C, Prat I, Urassa W, Kestens L
PLoS One . 2019 Jan; 14(1):e0209677. PMID: 30673713
Background: CD4 T-cell counts are still widely used to assess treatment eligibility and follow-up of HIV-infected patients. The World Health Organization (WHO) prequalification of in vitro diagnostics requested a manufacturer...
7.
Serum Levels of Soluble CD40 Ligand and Neopterin in HIV Coinfected Asymptomatic and Symptomatic Visceral Leishmaniasis Patients
Adriaensen W, Abdellati S, van Henten S, Gedamu Y, Diro E, Vogt F, et al.
Front Cell Infect Microbiol . 2019 Jan; 8:428. PMID: 30619775
Human Immunodeficiency Virus (HIV) co-infection drastically increases the risk of developing overt visceral leishmaniasis (VL). The asymptomatic infection window constitutes an opportunity to identify those HIV patients at highest risk...
8.
Modulation of innate immune responses at birth by prenatal malaria exposure and association with malaria risk during the first year of life
Natama H, Moncunill G, Rovira-Vallbona E, Sanz H, Sorgho H, Aguilar R, et al.
BMC Med . 2018 Nov; 16(1):198. PMID: 30384846
Background: Factors driving inter-individual differences in immune responses upon different types of prenatal malaria exposure (PME) and subsequent risk of malaria in infancy remain poorly understood. In this study, we...
9.
Syphilis reinfection is associated with an attenuated immune profile in the same individual: a prospective observational cohort study
Kenyon C, Osbak K, Crucitti T, Kestens L
BMC Infect Dis . 2018 Sep; 18(1):479. PMID: 30253745
Background: Ascertaining if the clinical and immunological response to repeat syphilis differs from that in initial syphilis may assist in designing optimal syphilis screening strategies and vaccine design. Methods: We...
10.
Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses
Chissumba R, Luciano A, Namalango E, Bauer A, Bhatt N, Wahren B, et al.
Immunobiology . 2018 Aug; 223(12):792-801. PMID: 30121146
Little is known about regulatory CD4 T cells (Tregs) in the context of HIV vaccines. Tregs can be differentiated into resting (FoxP3CD45RA - rTregs), activated (FoxP3CD45RA - aTregs) and memory...