Lu-Zhong Xu
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Explore the profile of Lu-Zhong Xu including associated specialties, affiliations and a list of published articles.
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7
Citations
44
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0
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Recent Articles
1.
Xu H, Yu J, Xu L, Fu J
J Neurol Sci
. 2016 Mar;
363:147-52.
PMID: 27000241
The present study was to investigate whether Z-guggulsterone had the regulatory effect on the activity and expression of P-glycoprotein in rat brain microvessel endothelial cells (rBMECs) and in rat brain....
2.
Xu H, Shen Z, Fu J, Xu L
Phytomedicine
. 2014 Aug;
21(11):1221-9.
PMID: 25172783
Our previous study has shown co-administration of guggulsterone resulted in significant increase in chemosensitivity of multidrug-resistant human breast cancer MCF-7/DOX cells to doxorubicin (DOX) in vitro. The present study was...
3.
Xu H, Xu L, Mao X, Fu J
Phytomedicine
. 2014 Apr;
21(7):1004-9.
PMID: 24680616
The purpose of this study was to investigate the effects of guggulsterone on cyclooxygenase-2 and P-glycoprotein mediated drug resistance in imatinib-resistant K562 cells (K562/IMA). MTT cytotoxicity assay, flow cytometry, western...
4.
Chen X, Xu H, Xu L, Mao X, Li L
Eur J Pharmacol
. 2013 Sep;
718(1-3):24-9.
PMID: 24041929
Our previous studies found that guggulsterone could inhibit P-glycoprotein-mediated multidrug resistance in P-glycoprotein over-expressed human cancer cell lines. However, the effects of guggulsterone on the ;P-glycoprotein function and expression in...
5.
Xu H, Zheng L, Li L, Xu L, Fu J
Cancer Invest
. 2013 Jan;
31(2):156-66.
PMID: 23286531
We sought to evaluate the efficacy of elemene in cancer treatment. We searched the literature using several databases up to October 2011. Thirty-eight trials met inclusion criteria. The meta-analysis demonstrated...
6.
Xu H, Xu L, Li L, Fu J, Mao X
Eur J Pharmacol
. 2012 Sep;
694(1-3):39-44.
PMID: 22960326
Multidrug resistance (MDR) presents a serious problem in cancer chemotherapy. Our previous studies have shown that guggulsterone could reverse MDR through inhibiting the function and expression of P-glycoprotein (P-gp). The...
7.
Xu H, Li L, Fu J, Mao X, Xu L
Pharmacology
. 2012 May;
89(5-6):303-12.
PMID: 22573000
Background: Multidrug resistance (MDR) presents a problem in cancer chemotherapy, and developing new agents to overcome MDR is important. This study intends to investigate the reversal effect of -elemene on...