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Lovisa E Reinius

Explore the profile of Lovisa E Reinius including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 881
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Recent Articles
1.
Soderhall C, Reinius L, Salmenpera P, Gentile M, Acevedo N, Konradsen J, et al.
Clin Epigenetics . 2021 May; 13(1):106. PMID: 33971943
Background: Methylation of DNA at CpG sites is an epigenetic modification and a potential modifier of disease risk, possibly mediating environmental effects. Currently, DNA methylation is commonly assessed using specific...
2.
Muurinen M, Hannula-Jouppi K, Reinius L, Soderhall C, Merid S, Bergstrom A, et al.
Sci Rep . 2017 Nov; 7(1):15693. PMID: 29146936
Silver-Russell syndrome (SRS) is a growth retardation syndrome in which loss of methylation on chromosome 11p15 (11p15 LOM) and maternal uniparental disomy for chromosome 7 [UPD(7)mat] explain 20-60% and 10%...
3.
Geidenstam N, Magnusson M, Danielsson A, Gerszten R, Wang T, Reinius L, et al.
Int J Endocrinol . 2017 May; 2017:6490473. PMID: 28484491
. We investigated the relationship between circulating amino acid levels and obesity; to what extent weight loss followed by weight maintenance can correct amino acid abnormalities; and whether amino acids...
4.
James A, Reinius L, Verhoek M, Gomes A, Kupczyk M, Hammar U, et al.
Am J Respir Crit Care Med . 2015 Sep; 193(2):131-42. PMID: 26372680
Rationale: Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels. Objectives: To examine serum chitotriosidase activity and YKL-40 levels...
5.
Acevedo N, Reinius L, Vitezic M, Fortino V, Soderhall C, Honkanen H, et al.
Clin Epigenetics . 2015 Apr; 7:34. PMID: 25874017
Background: Age-related changes in DNA methylation occurring in blood leukocytes during early childhood may reflect epigenetic maturation. We hypothesized that some of these changes involve gene networks of critical relevance...
6.
Acevedo N, Reinius L, Greco D, Gref A, Orsmark-Pietras C, Persson H, et al.
Hum Mol Genet . 2014 Sep; 24(3):875-90. PMID: 25256354
Single-nucleotide polymorphisms (SNPs) in GSDMB (Gasdermin B) and ORMDL3 (ORMDL sphingolipid biosynthesis regulator 3) are strongly associated with childhood asthma, but the molecular alterations contributing to disease remain unknown. We...
7.
Hannula-Jouppi K, Muurinen M, Lipsanen-Nyman M, Reinius L, Ezer S, Greco D, et al.
Epigenetics . 2013 Nov; 9(3):351-65. PMID: 24247273
DNA methylation is a hallmark of genomic imprinting and differentially methylated regions (DMRs) are found near and in imprinted genes. Imprinted genes are expressed only from the maternal or paternal...
8.
Konradsen J, James A, Nordlund B, Reinius L, Soderhall C, Melen E, et al.
J Allergy Clin Immunol . 2013 May; 132(2):328-35.e5. PMID: 23628340
Background: Problematic severe childhood asthma includes a subgroup of patients who are resistant to therapy. The specific mechanisms involved are unknown, and novel biomarkers are required to facilitate treatment and...
9.
Reinius L, Gref A, Saaf A, Acevedo N, Joerink M, Kupczyk M, et al.
PLoS One . 2013 Feb; 8(1):e53877. PMID: 23372674
Asthma and allergy are complex disorders influenced by both inheritance and environment, a relationship that might be further clarified by epigenetics. Neuropeptide S Receptor 1 (NPSR1) has been associated with...
10.
Reinius L, Acevedo N, Joerink M, Pershagen G, Dahlen S, Greco D, et al.
PLoS One . 2012 Aug; 7(7):e41361. PMID: 22848472
Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be measured by a large number of methods, now even in a genome-wide manner for hundreds...