Louise B Thingholm
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Explore the profile of Louise B Thingholm including associated specialties, affiliations and a list of published articles.
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13
Citations
984
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Recent Articles
1.
Carlsen K, Thingholm L, Dempfle A, Malham M, Bang C, Franke A, et al.
PLoS One
. 2024 Dec;
19(12):e0311604.
PMID: 39666667
Background: The gut microbiome plays a crucial role in the pathogenesis and progression of inflammatory bowel disease (IBD). Understanding the dynamics of the gut microbiome in relation to treatment can...
2.
Malham M, Vestergaard M, Bataillon T, Villesen P, Dempfle A, Bang C, et al.
Inflamm Bowel Dis
. 2024 Aug;
31(2):501-513.
PMID: 39150994
Background: Pediatric-onset ulcerative colitis (pUC) represents a more aggressive disease phenotype compared with adult-onset UC. We hypothesized that this difference can, in part, be explained by the composition of the...
3.
Mirzayi C, Renson A, Zohra F, Elsafoury S, Geistlinger L, Kasselman L, et al.
Nat Med
. 2021 Nov;
27(11):1885-1892.
PMID: 34789871
The particularly interdisciplinary nature of human microbiome research makes the organization and reporting of results spanning epidemiology, biology, bioinformatics, translational medicine and statistics a challenge. Commonly used reporting guidelines for...
4.
Thingholm L, Bang C, Ruhlemann M, Starke A, Sicks F, Kaspari V, et al.
BMC Microbiol
. 2021 Oct;
21(1):276.
PMID: 34635060
Compared to the huge microbial diversity in most mammals, human gut microbiomes have lost diversity while becoming specialized for animal-based diets - especially compared to chimps, their genetically closest ancestors....
5.
von Huth S, Thingholm L, Kofoed P, Bang C, Ruhlemann M, Franke A, et al.
PLoS Negl Trop Dis
. 2021 Mar;
15(3):e0009232.
PMID: 33657123
Intestinal parasitic infections, caused by helminths and protozoa, are globally distributed and major causes of worldwide morbidity. The gut microbiota may modulate parasite virulence and host response upon infection. The...
6.
Kummen M, Thingholm L, Ruhlemann M, Holm K, Hansen S, Moitinho-Silva L, et al.
Gastroenterology
. 2021 Jan;
160(5):1784-1798.e0.
PMID: 33387530
Background & Aims: To influence host and disease phenotype, compositional microbiome changes, which have been demonstrated in patients with primary sclerosing cholangitis (PSC), must be accompanied by functional changes. We...
7.
Pryor R, Norvaisas P, Marinos G, Best L, Thingholm L, Quintaneiro L, et al.
Cell
. 2019 Sep;
178(6):1299-1312.e29.
PMID: 31474368
Metformin is the first-line therapy for treating type 2 diabetes and a promising anti-aging drug. We set out to address the fundamental question of how gut microbes and nutrition, key...
8.
Thingholm L, Ruhlemann M, Koch M, Fuqua B, Laucke G, Boehm R, et al.
Cell Host Microbe
. 2019 Aug;
26(2):252-264.e10.
PMID: 31399369
Obesity and type 2 diabetes (T2D) are metabolic disorders that are linked to microbiome alterations. However, their co-occurrence poses challenges in disentangling microbial features unique to each condition. We analyzed...
9.
Ruhlemann M, Degenhardt F, Thingholm L, Wang J, Skieceviciene J, Rausch P, et al.
Gut Microbes
. 2017 Aug;
9(1):68-75.
PMID: 28816579
Factors shaping the human intestinal microbiota range from environmental influences, like smoking and exercise, over dietary patterns and disease to the host's genetic variation. Recently, we could show in a...
10.
Henstrom M, Diekmann L, Bonfiglio F, Hadizadeh F, Kuech E, von Kockritz-Blickwede M, et al.
Gut
. 2016 Nov;
67(2):263-270.
PMID: 27872184
Objective: IBS is a common gut disorder of uncertain pathogenesis. Among other factors, genetics and certain foods are proposed to contribute. Congenital sucrase-isomaltase deficiency (CSID) is a rare genetic form...