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Louise A E Brown

Explore the profile of Louise A E Brown including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 464
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Recent Articles
1.
Sharrack N, Knott K, Gulsin G, Kotecha T, Brown L, Yeo J, et al.
Sci Rep . 2024 Nov; 14(1):27280. PMID: 39516499
Metformin is an antihyperglycemic used to treat type 2 diabetes mellitus (T2DM). Patients with T2DM are at increased risk of cardiovascular disease. We explored the association between metformin use and...
2.
Crane J, Joy G, Knott K, Augusto J, Lau C, Bhuva A, et al.
JACC Cardiovasc Imaging . 2024 Aug; 17(11):1305-1316. PMID: 39115498
Background: Coronary microvascular function is impaired in patients with obesity, contributing to myocardial dysfunction and heart failure. Bariatric surgery decreases cardiovascular mortality and heart failure, but the mechanisms are unclear....
3.
Sharrack N, Brown L, Farley J, Wahab A, Jex N, Thirunavukarasu S, et al.
J Cardiovasc Magn Reson . 2024 Aug; 26(2):101073. PMID: 39096970
Background: Patients with diabetes mellitus (DM) and heart failure (HF) have worse outcomes than normoglycemic HF patients. Cardiovascular magnetic resonance (CMR) can identify ischemic heart disease (IHD) and quantify coronary...
4.
Gorecka M, Craven T, Jex N, Chew P, Dobson L, Brown L, et al.
Int J Cardiovasc Imaging . 2024 May; 40(7):1543-1553. PMID: 38780711
Purpose: Exercise imaging using current modalities can be challenging. This was patient focused study to establish the feasibility and reproducibility of exercise-cardiovascular magnetic resonance imaging (EX-CMR) acquired during continuous in-scanner...
5.
Gorecka M, Cole C, Bissell M, Craven T, Chew P, Dobson L, et al.
J Magn Reson Imaging . 2024 Feb; 60(6):2378-2392. PMID: 38344930
Background: Four-dimensional-flow cardiac MR (4DF-MR) offers advantages in primary mitral regurgitation. The relationship between 4DF-MR-derived mitral regurgitant volume (MR-Rvol) and the post-operative left ventricular (LV) reverse remodeling has not yet...
6.
Farooq M, Brown L, Fitzpatrick A, Broadbent D, Wahab A, Klassen J, et al.
Sci Rep . 2023 Sep; 13(1):14640. PMID: 37669972
Left ventricular fibrosis can be identified by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) in some veteran athletes. We aimed to investigate prevalence of ventricular fibrosis in veteran athletes...
7.
Craven T, Chew P, Dobson L, Gorecka M, Parent M, Brown L, et al.
J Cardiovasc Magn Reson . 2023 Jul; 25(1):43. PMID: 37496072
Background: When feasible, guidelines recommend mitral valve repair (MVr) over mitral valve replacement (MVR) to treat primary mitral regurgitation (MR), based upon historic outcome studies and transthoracic echocardiography (TTE) reverse...
8.
Brown L, Gulsin G, Onciul S, Broadbent D, Yeo J, Wood A, et al.
Eur Heart J Cardiovasc Imaging . 2022 Dec; 24(4):426-434. PMID: 36458882
Aims: Recently developed in-line automated cardiovascular magnetic resonance (CMR) myocardial perfusion mapping has been shown to be reproducible and comparable with positron emission tomography (PET), and can be easily integrated...
9.
Brown L, Wahab A, Ikongo E, Saunderson C, Jex N, Thirunavukarasu S, et al.
Eur Heart J Cardiovasc Imaging . 2022 Oct; 24(1):38-45. PMID: 36285884
Aims: The 2016 European Society of Cardiology Heart Failure Guidelines defined a new category: heart failure with mid-range ejection fraction (HFmrEF) of 40-49%. This new category was highlighted as having...
10.
Das A, Kelly C, Teh I, Nguyen C, Brown L, Chowdhary A, et al.
Eur Heart J Cardiovasc Imaging . 2021 Oct; 23(3):352-362. PMID: 34694365
Aims: Microvascular dysfunction in hypertrophic cardiomyopathy (HCM) is predictive of clinical decline, however underlying mechanisms remain unclear. Cardiac diffusion tensor imaging (cDTI) allows in vivo characterization of myocardial microstructure by...