Louis S Premkumar
Overview
Explore the profile of Louis S Premkumar including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
1580
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Recent Articles
1.
Louis-Gray K, Tupal S, Premkumar L
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077412
The most common medicinal claims for cannabis are relief from chronic pain, stimulation of appetite, and as an antiemetic. However, the mechanisms by which cannabis reduces pain and prevents nausea...
2.
Baskaran P, Mohandass A, Gustafson N, Bennis J, Louis S, Alexander B, et al.
Pain
. 2022 Aug;
164(4):782-790.
PMID: 36001079
Painful diabetic peripheral neuropathy (PDPN) is one of the major complications of diabetes. Currently, centrally acting drugs and topical analgesics are used for treating PDPN. These drugs have adverse effects;...
3.
Nemenov M, Singleton J, Premkumar L
Curr Diabetes Rev
. 2021 Dec;
18(5):e081221198649.
PMID: 34879806
The cutaneous mechanisms that trigger spontaneous neuropathic pain in diabetic peripheral neuropathy (PDPN) are far from clear. Two types of nociceptors are found within the epidermal and dermal skin layers....
4.
Feng L, Uteshev V, Premkumar L
Int J Mol Sci
. 2019 Apr;
20(9).
PMID: 31027359
The nucleus of the solitary tract (NTS) receives visceral information via the solitary tract (ST) that comprises the sensory components of the cranial nerves VII, IX and X. The Transient...
5.
Pabbidi M, Premkumar L
J Diabetes Treat
. 2019 Jan;
2017(4).
PMID: 30613832
Objective: 1.1.Transient Receptor Potential (Vanilloid 1) TRPV1 and (Melastatin 8) TRPM8 are heat and cold sensing non-selective cation channels, respectively. We sought to correlate the modulation of TRPV1- and TRPM8-mediated...
6.
Samineni V, Premkumar L, Faingold C
Pain
. 2017 Mar;
158(7):1241-1253.
PMID: 28328571
Neuropathic pain is a debilitating pathological condition that is poorly understood. Recent evidence suggests that abnormal central processing occurs during the development of neuropathic pain induced by the cancer chemotherapeutic...
7.
Khare P, Jagtap S, Jain Y, Baboota R, Mangal P, Boparai R, et al.
Biofactors
. 2016 Feb;
42(2):201-11.
PMID: 26893251
Cinnamaldehyde, a bioactive component of cinnamon, is increasingly gaining interest for its preventive and therapeutic effects against metabolic complications like type-2 diabetes. This study is an attempt to understand the...
8.
Premkumar L
ACS Chem Neurosci
. 2014 Jun;
5(11):1117-30.
PMID: 24926802
To date, 28 mammalian transient receptor potential (TRP) channels have been cloned and characterized. They are grouped into six subfamilies on the basis of their amino acid sequence homology: TRP...
9.
Baboota R, Murtaza N, Jagtap S, Singh D, Karmase A, Kaur J, et al.
J Nutr Biochem
. 2014 Jun;
25(9):893-902.
PMID: 24917046
Obesity is a global health problem and recently it has been seen as a growing concern for developing countries. Several bioactive dietary molecules have been associated with amelioration of obesity...
10.
Premkumar L, Pabbidi R
Cell Biochem Biophys
. 2013 Jun;
67(2):373-83.
PMID: 23722999
The prevalence of diabetes has reached epidemic proportions. There are two forms of diabetes: type 1 diabetes mellitus is due to auto-immune-mediated destruction of pancreatic β-cells resulting in absolute insulin...