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Loretta De Chiara

Explore the profile of Loretta De Chiara including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 226
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Recent Articles
1.
Gallego-Garcia P, Estevez-Gomez N, De Chiara L, Alvarino P, Juiz-Gonzalez P, Torres-Beceiro I, et al.
J Med Virol . 2024 Jun; 96(7):e29773. PMID: 38940448
The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study,...
2.
Gallego-Garcia P, Estevez-Gomez N, De Chiara L, Alvarino P, Juiz-Gonzalez P, Torres-Beceiro I, et al.
medRxiv . 2024 Mar; PMID: 38463998
The dynamics of SARS-CoV-2 transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and...
3.
Gallardo-Gomez M, Costas-Rios L, Garcia-Prieto C, Alvarez-Rodriguez L, Bujanda L, Barrero M, et al.
Mol Oncol . 2023 Dec; 18(11):2696-2713. PMID: 38129291
The clinical relevance of the colorectal cancer serrated pathway is evident, but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway...
4.
Gallardo-Gomez M, Rodriguez-Girondo M, Planell N, Moran S, Bujanda L, Etxart A, et al.
Clin Epigenetics . 2023 Oct; 15(1):157. PMID: 37794510
Background: Early detection has proven to be the most effective strategy to reduce the incidence and mortality of colorectal cancer (CRC). Nevertheless, most current screening programs suffer from low participation...
5.
De Chiara L, Barcia-Castro L, Gallardo-Gomez M, Paez de la Cadena M, Martinez-Zorzano V, Rodriguez-Berrocal F, et al.
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230486
Fecal hemoglobin immunodetection (FIT) in combination with endoscopy has been implemented to reduce mortality from colorectal cancer (CRC), although there are issues that can be improved in relation to participation...
6.
Gallego-Garcia P, Varela N, Estevez-Gomez N, De Chiara L, Fernandez-Silva I, Valverde D, et al.
Virus Evol . 2022 Mar; 8(1):veac008. PMID: 35242361
A detailed understanding of how and when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs is crucial for designing effective prevention measures. Other than contact tracing, genome sequencing provides...
7.
Alvarez H, Ruiz-Mateos E, Juiz-Gonzalez P, Vitalle J, Vieitez I, Vazquez-Friol M, et al.
Microorganisms . 2022 Jan; 10(1). PMID: 35056592
Intra-host evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in cases with persistent coronavirus disease 2019 (COVID-19). In this study, we describe a severely immunosuppressed individual...
8.
Carvalho-Correia E, Calcada C, Branca F, Estevez-Gomez N, De Chiara L, Varela N, et al.
Biomedicines . 2021 Oct; 9(10). PMID: 34680431
Extensive transmission of SARS-CoV-2 during the COVID-19 pandemic allowed the generation of thousands of mutations within its genome. While several of these become rare, others largely increase in prevalence, potentially...
9.
Gallardo-Gomez M, De Chiara L, Alvarez-Chaver P, Cubiella J
Expert Rev Anticancer Ther . 2021 Jan; 21(7):723-738. PMID: 33507120
: Colorectal cancer (CRC) is one of the most important health problems in the Western world. In order to reduce the burden of the disease, two strategies are proposed: screening...
10.
De Chiara L, Leiro-Fernandez V, Rodriguez-Girondo M, Valverde D, Botana-Rial M, Fernandez-Villar A
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33287451
Different methodological approaches are available to assess DNA methylation biomarkers. In this study, we evaluated two sodium bisulfite conversion-dependent methods, namely pyrosequencing and methylation-specific qPCR (MS-qPCR), with the aim of...