Lorenzo Silengo
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Explore the profile of Lorenzo Silengo including associated specialties, affiliations and a list of published articles.
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84
Citations
2960
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Recent Articles
11.
Fusella F, Secli L, Busso E, Krepelova A, Moiso E, Rocca S, et al.
Nat Commun
. 2017 Nov;
8(1):1636.
PMID: 29158506
NF-κB is a transcription factor involved in the regulation of multiple physiological and pathological cellular processes, including inflammation, cell survival, proliferation, and cancer cell metastasis. NF-κB is frequently hyperactivated in...
12.
Ingoglia G, Sag C, Rex N, De Franceschi L, Vinchi F, Cimino J, et al.
Data Brief
. 2017 Jun;
13:69-76.
PMID: 28560284
The data presented in this article are related to the research article entitled (G. Ingoglia, C. M. Sag, N. Rex, L. De Franceschi, F. Vinchi, J. Cimino, S. Petrillo, S....
13.
Ingoglia G, Sag C, Rex N, De Franceschi L, Vinchi F, Cimino J, et al.
Free Radic Biol Med
. 2017 Apr;
108:452-464.
PMID: 28400318
Heart failure is a leading cause of morbidity and mortality in patients affected by different disorders associated to intravascular hemolysis. The leading factor is the presence of pathologic amount of...
14.
Fagoonee S, Picco G, Orso F, Arrigoni A, Longo D, Forni M, et al.
Oncotarget
. 2017 Jan;
8(6):10007-10024.
PMID: 28052020
Epithelial splicing regulatory protein 1 (ESRP1) is an epithelial cell-specific RNA binding protein that controls several key cellular processes, like alternative splicing and translation. Previous studies have demonstrated a tumor...
15.
Chiabrando D, Castori M, Di Rocco M, Ungelenk M, Giesselmann S, Di Capua M, et al.
PLoS Genet
. 2016 Dec;
12(12):e1006461.
PMID: 27923065
Pain is necessary to alert us to actual or potential tissue damage. Specialized nerve cells in the body periphery, so called nociceptors, are fundamental to mediate pain perception and humans...
16.
Fagoonee S, Famulari E, Silengo L, Camussi G, Altruda F
Stem Cells Dev
. 2016 Aug;
25(20):1471-1482.
PMID: 27503633
Hepatocytes constitute the main bulk of the liver and perform several essential functions. After injury, the hepatocytes have a remarkable capacity to regenerate and restore functionality. However, in some cases,...
17.
Lorenzo N, Altruda F, Silengo L, Del Carmen Dominguez M
Clin Exp Med
. 2016 May;
17(2):209-216.
PMID: 27160252
Induction of tolerance to autoantigens in vivo is a complex process that involves several mechanisms such as the induction of regulatory T cells and changes in the cytokine and chemokine...
18.
Fagoonee S, Famulari E, Silengo L, Tolosano E, Altruda F
PLoS One
. 2015 Sep;
10(8):e0136762.
PMID: 26323094
One of the major hurdles in liver gene and cell therapy is availability of ex vivo-expanded hepatocytes. Pluripotent stem cells are an attractive alternative. Here, we show that hepatocyte precursors...
19.
Fiorito V, Forni M, Silengo L, Altruda F, Tolosano E
Antioxid Redox Signal
. 2015 Jun;
23(18):1410-23.
PMID: 26067085
Aims: The maintenance of heme homeostasis, mucosa cell renewal, and redox environment in the intestine is essential to permit digestion, absorption, cell proliferation, cell apoptosis, and immune response and to...
20.
Mercurio S, Aspesi A, Silengo L, Altruda F, Dianzani I, Chiabrando D
Eur J Haematol
. 2015 Jun;
96(4):367-74.
PMID: 26058344
Diamond-Blackfan anemia (DBA) is a congenital pure red cell aplasia often associated with skeletal malformations. Mutations in ribosomal protein coding genes, mainly in RPS19, account for the majority of DBA...