Lorenz Kadletz-Wanke
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Explore the profile of Lorenz Kadletz-Wanke including associated specialties, affiliations and a list of published articles.
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27
Citations
86
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Recent Articles
1.
Kandathil S, Peter Truta I, Kadletz-Wanke L, Heiduschka G, Stoiber S, Kenner L, et al.
J Pers Med
. 2024 Feb;
14(2).
PMID: 38392590
Background: Young patients with tongue squamous cell carcinoma (TSCC) mostly lack typical prognostic markers and face a dire prognosis. The aim of this study was to analyze the prognostic relevance...
2.
Kandathil S, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic F
J Cancer Res Clin Oncol
. 2024 Jan;
150(2):56.
PMID: 38291202
Purpose: Human papilloma virus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) displays distinct epidemiological, clinical, and molecular characteristics compared to the negative counterpart. Alterations in autophagy play an important...
3.
Schnoell J, Sparr C, Al-Gboore S, Haas M, Brkic F, Kadletz-Wanke L, et al.
Invest New Drugs
. 2023 Nov;
41(6):842-850.
PMID: 37934325
Alterations in the DNA damage response play a crucial role in radio- and chemoresistance of neoplastic cells. Activation of the Ataxia telangiectasia and Rad3-related (ATR) pathway is an important DNA...
4.
Haas M, Lein A, Fuereder T, Schnoell J, Brkic F, Liu D, et al.
Invest New Drugs
. 2023 Aug;
41(5):727-736.
PMID: 37603206
Purpose: First-line immune checkpoint blockade has improved the prognosis of recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC), but response rates remain low. In this study, we...
5.
Haas M, Lein A, Fuereder T, Schnoell J, Brkic F, Campion N, et al.
Int Immunopharmacol
. 2023 Aug;
123:110799.
PMID: 37598631
Introduction: Thyroid function is frequently impaired in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). In patients treated with pembrolizumab, immune-related adverse events (irAEs) of the thyroid are common....
6.
Varatanovic S, Stoiber S, Haas M, Lein A, Kadletz-Wanke L, Brkic F
J Cancer Res Clin Oncol
. 2023 Aug;
149(16):14691-14699.
PMID: 37587308
Purpose: Gamma-secretase inhibitor MK0752 has shown a high therapeutic potential in different solid malignant tumors. Up to now, its antineoplastic effects were not investigated in head and neck squamous cell...
7.
Scheiflinger A, Al-Gboore S, Jank B, Brkic F, Kadletz-Wanke L, Kenner L, et al.
J Cancer Res Clin Oncol
. 2023 Jun;
149(12):10675-10683.
PMID: 37308746
Introduction: Head and neck squamous cell carcinoma (HNSCC) is among the most common cancers in the world with a low survival rate and common diagnosis at late stages. Deubiquitination of...
8.
Jank B, Schnoell J, Kladnik K, Sparr C, Haas M, Gurnhofer E, et al.
Oral Dis
. 2023 May;
30(3):1114-1127.
PMID: 37154295
Objectives: The transforming growth factor-Beta (TGF-ß) pathway may be involved in the radioresistance of head and neck squamous cell carcinoma (HNSCC). This study analyzed TGF-ß receptor 1 (TGFBR1) expression in...
9.
Stoiber S, Brkic F, Maier T, Schnoell J, Gurnhofer E, Heiduschka G, et al.
J Cancer Res Clin Oncol
. 2023 Apr;
149(10):7743-7750.
PMID: 37010585
Purpose: The evolutionary-conserved Wnt/β-CATENIN (WBC) pathway has been implicated in the pathogenesis of different solid malignant tumors. We evaluated the prognostic relevance of β-CATENIN, a pivotal mediator of WBC activation,...
10.
Haas M, Lein A, Fuereder T, Brkic F, Schnoell J, Liu D, et al.
Nutrients
. 2023 Feb;
15(4).
PMID: 36839241
Malnutrition is a frequent comorbidity in head and neck cancer patients and has been shown to impair immunotherapy response in other cancer types. The geriatric nutritional risk index (GNRI) assesses...