Lorena Pantano
Overview
Explore the profile of Lorena Pantano including associated specialties, affiliations and a list of published articles.
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43
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3288
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Recent Articles
1.
Li W, Sparks R, Sun C, Yang Y, Pantano L, Kirchner R, et al.
Nat Commun
. 2025 Mar;
16(1):2109.
PMID: 40025044
Hepatic stellate cells (HSCs) are activated with chronic liver injury and transdifferentiate into myofibroblasts, which produce excessive extracellular matrices that form the fibrotic scar. While the progression of fibrosis is...
2.
Parra R, Wass M, Munholland S, Wiper M, Kovats D, Pantano L, et al.
Bioinform Adv
. 2025 Feb;
5(1):vbae204.
PMID: 39927293
The first ISCB LGBTQI+ Symposium, held during Pride Month in 2024, marked a significant milestone for the International Society for Computational Biology (ISCB) community to promote diversity. This event aimed...
3.
Anand R, Layer J, Heja D, Hirose T, Lassiter G, Firl D, et al.
Nature
. 2023 Oct;
622(7982):393-401.
PMID: 37821590
Recent human decedent model studies and compassionate xenograft use have explored the promise of porcine organs for human transplantation. To proceed to human studies, a clinically ready porcine donor must...
4.
Blaser M, Buffolo F, Halu A, Turner M, Schlotter F, Higashi H, et al.
Circulation
. 2023 Jul;
148(8):661-678.
PMID: 37427430
Background: Fewer than 50% of patients who develop aortic valve calcification have concomitant atherosclerosis, implying differential pathogenesis. Although circulating extracellular vesicles (EVs) act as biomarkers of cardiovascular diseases, tissue-entrapped EVs...
5.
Li W, Chen J, Sun C, Sparks R, Pantano L, Rahman R, et al.
Elife
. 2022 May;
11.
PMID: 35617485
Chronic liver injury causes fibrosis, characterized by the formation of scar tissue resulting from excessive accumulation of extracellular matrix (ECM) proteins. Hepatic stellate cell (HSC) myofibroblasts are the primary cell...
6.
Yang Y, Santos D, Pantano L, Knipe R, Abe E, Logue A, et al.
Am J Respir Cell Mol Biol
. 2022 Apr;
67(1):36-49.
PMID: 35377835
Idiopathic pulmonary fibrosis is a progressive lung disease with limited therapeutic options that is characterized by pathological fibroblast activation and aberrant lung remodeling with scar formation. YAP (Yes-associated protein) is...
7.
Pantano L, Agyapong G, Shen Y, Zhuo Z, Fernandez-Albert F, Rust W, et al.
Sci Rep
. 2021 Sep;
11(1):18045.
PMID: 34508113
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. In adults with NAFLD, fibrosis can develop and progress to liver cirrhosis and liver failure. However,...
8.
Creus-Muncunill J, Guisado-Corcoll A, Venturi V, Pantano L, Escaramis G, Garcia de Herreros M, et al.
Acta Neuropathol
. 2021 Feb;
141(4):565-584.
PMID: 33547932
Progressive motor alterations and selective death of striatal medium spiny neurons (MSNs) are key pathological hallmarks of Huntington's disease (HD), a neurodegenerative condition caused by a CAG trinucleotide repeat expansion...
9.
Gupta H, Rubio M, Sitoe A, Varo R, Cistero P, Madrid L, et al.
Emerg Infect Dis
. 2021 Jan;
27(2):430-442.
PMID: 33496227
Severe malaria (SM) is a major public health problem in malaria-endemic countries. Sequestration of Plasmodium falciparum-infected erythrocytes in vital organs and the associated inflammation leads to organ dysfunction. MicroRNAs (miRNAs),...
10.
Podnar J, Pantano L, Zeller M, Kolling F, Zhang Y, Alekseyev Y, et al.
J Biomol Tech
. 2020 Aug;
31(3):88-93.
PMID: 32831655
Sanger sequencing remains an essential tool utilized by researchers. Despite competition from commercial sequencing providers, many academic sequencing core facilities continue to offer these services based on a model of...