Lorena Landuzzi
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Explore the profile of Lorena Landuzzi including associated specialties, affiliations and a list of published articles.
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76
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1264
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Recent Articles
1.
Landuzzi L, Ruzzi F, Lollini P, Scotlandi K
Int J Mol Sci
. 2025 Feb;
26(4).
PMID: 40004005
Chondrosarcoma (CS), the second most common malignant bone tumor after osteosarcoma, accounts for 20-30% of all malignant bone tumors. It mainly affects adults, middle-aged, and elderly people. The CS family...
2.
Pasello M, Laginestra M, Manara M, Landuzzi L, Ruzzi F, Maioli M, et al.
J Cell Commun Signal
. 2024 Nov;
18(3):e12047.
PMID: 39524141
Ewing sarcoma (EwS), a highly aggressive malignancy affecting children and young adults, is primarily driven by a distinctive oncogenic fusion, the EWSR1-ETS, whose activity is a key source of epigenetic...
3.
Ruzzi F, Cappello C, Semprini M, Scalambra L, Angelicola S, Pittino O, et al.
Cell Commun Signal
. 2024 Oct;
22(1):489.
PMID: 39394159
Lipid rafts are dynamic microdomains enriched with cholesterol and sphingolipids that play critical roles in cellular processes by organizing and concentrating specific proteins involved in signal transduction. The interplay between...
4.
Landuzzi L, Ruzzi F, Pellegrini E, Lollini P, Scotlandi K, Manara M
Cells
. 2024 Feb;
13(3.
PMID: 38334625
IL-1 family members have multiple pleiotropic functions affecting various tissues and cells, including the regulation of the immune response, hematopoietic homeostasis, bone remodeling, neuronal physiology, and synaptic plasticity. Many of...
5.
Manara M, Manferdini C, Cristalli C, Carrabotta M, Santi S, De Feo A, et al.
Cancer Immunol Res
. 2023 Dec;
12(2):247-260.
PMID: 38051221
Ewing sarcoma (EWS) is the second most common pediatric bone tumor. The EWS tumor microenvironment is largely recognized as immune-cold, with macrophages being the most abundant immune cells and their...
6.
Landuzzi L, Manara M, Pazzaglia L, Lollini P, Scotlandi K
Cancers (Basel)
. 2023 Aug;
15(15).
PMID: 37568703
Synovial sarcoma (SyS) is a rare aggressive soft tissue sarcoma carrying the chromosomal translocation t(X;18), encoding the fusion transcript SS18::SSX. The fusion oncoprotein interacts with both BAF enhancer complexes and...
7.
Landuzzi L, Ruzzi F, Lollini P, Scotlandi K
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765545
Synovial sarcomas (SyS) are rare malignant tumors predominantly affecting children, adolescents, and young adults. The genetic hallmark of SyS is the t(X;18) translocation encoding the SS18-SSX fusion gene. The fusion...
8.
Ruzzi F, Angelicola S, Landuzzi L, Nironi E, Semprini M, Scalambra L, et al.
Transl Lung Cancer Res
. 2022 Dec;
11(11):2216-2229.
PMID: 36519016
Background: ROS1 fusions are driver molecular alterations in 1-2% of non-small cell lung cancers (NSCLCs). Several tyrosine kinase inhibitors (TKIs) have shown high efficacy in patients whose tumors harbour a...
9.
Ruzzi F, Palladini A, Clemmensen S, Strobaek A, Buijs N, Domeyer T, et al.
Biomedicines
. 2022 Oct;
10(10).
PMID: 36289916
Vaccines are a promising therapeutic alternative to monoclonal antibodies against HER-2+ breast cancer. We present the preclinical activity of an ES2B-C001, a VLP-based vaccine being developed for human breast cancer...
10.
Sorrentino C, DAntonio L, Ciummo S, Fieni C, Landuzzi L, Ruzzi F, et al.
J Hematol Oncol
. 2022 Oct;
15(1):145.
PMID: 36224639
Background: Metastatic prostate cancer (PC) is a leading cause of cancer death in men worldwide. Targeting of the culprits of disease progression is an unmet need. Interleukin (IL)-30 promotes PC...