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Lonneke M E Leijten

Explore the profile of Lonneke M E Leijten including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 339
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Recent Articles
1.
Mols V, Lamers M, Leijten L, Breugem T, van de Bildt M, van den Doel P, et al.
J Virol . 2023 May; 97(5):e0059623. PMID: 37154754
No abstract available.
2.
Sooksawasdi Na Ayudhya S, Sips G, Bogers S, Leijten L, Laksono B, Smeets L, et al.
J Clin Virol . 2022 May; 152:105190. PMID: 35640402
Background: Enterovirus-D68 (EV-D68) predominantly causes respiratory disease. However, EV-D68 infections also have been associated with central nervous system (CNS) complications, most specifically acute flaccid myelitis (AFM). Diagnosing EV-D68-associated CNS disease...
3.
Siegers J, Short K, Leijten L, de Graaf M, Spronken M, Schrauwen E, et al.
J Virol . 2014 Jan; 88(8):4595-9. PMID: 24478425
We determined the pattern of attachment of the avian-origin H7N9 influenza viruses A/Anhui/1/2013 and A/Shanghai/1/2013 to the respiratory tract in ferrets, macaques, mice, pigs, and guinea pigs and compared it...
4.
van Riel D, Leijten L, de Graaf M, Siegers J, Short K, Spronken M, et al.
Am J Pathol . 2013 Sep; 183(4):1137-1143. PMID: 24029490
Influenza A viruses from animal reservoirs have the capacity to adapt to humans and cause influenza pandemics. The occurrence of an influenza pandemic requires efficient virus transmission among humans, which...
5.
Reperant L, van de Bildt M, van Amerongen G, Leijten L, Watson S, Palser A, et al.
J Virol . 2011 Nov; 86(2):1158-65. PMID: 22090101
Highly pathogenic avian influenza virus (HPAIV) H5N1 can infect mammals via the intestine; this is unusual since influenza viruses typically infect mammals via the respiratory tract. The dissemination of HPAIV...
6.
van Riel D, Leijten L, van der Eerden M, Hoogsteden H, Boven L, Lambrecht B, et al.
PLoS Pathog . 2011 Jul; 7(6):e1002099. PMID: 21731493
Highly pathogenic avian influenza virus (HPAIV) of the subtype H5N1 causes severe, often fatal pneumonia in humans. The pathogenesis of HPAIV H5N1 infection is not completely understood, although the alveolar...
7.
Smits S, van den Brand J, de Lang A, Leijten L, van IJcken W, van Amerongen G, et al.
J Virol . 2011 Feb; 85(9):4234-45. PMID: 21325418
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), caused by influenza A virus H5N1 and severe acute respiratory syndrome coronavirus (SARS-CoV), supposedly depend on activation of the oxidative-stress...
8.
van den Brand J, Stittelaar K, van Amerongen G, van de Bildt M, Leijten L, Kuiken T, et al.
Emerg Infect Dis . 2010 Oct; 16(11):1745-7. PMID: 21029533
To demonstrate that pandemic (H1N1) 2009 virus may cause respiratory disease in cats, we intratracheally infected cats. Diffuse alveolar damage developed. Seroconversion of sentinel cats indicated cat-to-cat virus transmission. Unlike...
9.
van Riel D, den Bakker M, Leijten L, Chutinimitkul S, Munster V, de Wit E, et al.
Am J Pathol . 2010 Feb; 176(4):1614-8. PMID: 20167867
Influenza viruses vary markedly in their efficiency of human-to-human transmission. This variation has been speculated to be determined in part by the tropism of influenza virus for the human upper...
10.
Wan H, van Helden-Meeuwsen C, Garlanda C, Leijten L, Maina V, Khan N, et al.
J Leukoc Biol . 2008 Aug; 84(5):1346-52. PMID: 18685085
Pentraxin 3 (PTX3) is an acute-phase response protein that initiates innate immunity against diverse microorganisms. It is produced in response to proinflammatory stimuli by many cell types including myeloid cells....