Longmin Chen
Overview
Explore the profile of Longmin Chen including associated specialties, affiliations and a list of published articles.
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13
Citations
123
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0
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Recent Articles
1.
Chen L, Zhou Q, Fang X, Xu Q, Zou Y, Zhang J
Int J Nanomedicine
. 2024 May;
19:4411-4427.
PMID: 38774028
Background: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease characterized by synovial inflammation and joint destruction. Despite progress in RA therapy, it remains difficult to achieve long-term remission...
2.
Zou Y, Zhang J, Sun F, Xu Q, Chen L, Luo X, et al.
Mol Med
. 2024 Feb;
30(1):23.
PMID: 38317106
Background: Fluvoxamine is one of the selective serotonin reuptake inhibitors (SSRIs) that are regarded as the first-line drugs to manage mental disorders. It has been also recognized with the potential...
3.
Zhang J, Chen L, Xu Q, Zou Y, Sun F, Zhou Q, et al.
Cell Death Dis
. 2023 Nov;
14(11):737.
PMID: 37957143
SUMOylation is an evolutionary conserved regulatory mechanism, in which Ubc9 is the only E2 conjugating enzyme. Previous studies demonstrated that SUMOylation is involved in multiple biological processes, but its role...
4.
Zhang J, Zou Y, Chen L, Sun F, Xu Q, Zhou Q, et al.
Nat Commun
. 2023 Sep;
14(1):5977.
PMID: 37749140
The regulation of autoimmunity against pancreatic islet β cells for type 1 diabetes (T1D) onset is still unclear. NOD/ShiLtJ (NOD) mice are prone to the onset of autoimmune diabetes, but...
5.
Li J, Zhao J, Chen L, Gao H, Zhang J, Wang D, et al.
Brain Behav Immun
. 2022 Nov;
108:32-44.
PMID: 36343753
Background: Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons (DA) and the accumulation of Lewy body deposits composed of alpha-Synuclein (α-Syn), which act as antigenic epitopes to...
6.
Zhang J, Zou Y, Chen L, Xu Q, Wang Y, Xie M, et al.
Front Immunol
. 2022 Jun;
13:902318.
PMID: 35757774
Asthma is a multifactorial disorder characterized by the airway chronic inflammation, hyper-responsiveness (AHR), remodeling, and reversible obstruction. Although asthma is known as a heterogeneous group of diseases with various clinical...
7.
Li J, Chen L, Qin Q, Wang D, Zhao J, Gao H, et al.
Neurobiol Dis
. 2022 Jan;
163:105605.
PMID: 34973450
Parkinson's disease (PD) is characterized by impaired mitochondrial function and decreased ATP levels. Aerobic glycolysis and lactate production have been shown to be upregulated in dopaminergic neurons to sustain ATP...
8.
Zhang J, Chen L, Xiong F, Zhang S, Huang K, Zhang Z, et al.
Mol Immunol
. 2021 Jul;
137:41.
PMID: 34214827
No abstract available.
9.
Chen L, Zhang J, Zou Y, Wang F, Li J, Sun F, et al.
Cell Death Differ
. 2021 Jan;
28(6):1880-1899.
PMID: 33462408
Kdm2a catalyzes H3K36me2 demethylation to play an intriguing epigenetic regulatory role in cell proliferation, differentiation, and apoptosis. Herein we found that myeloid-specific knockout of Kdm2a (LysM-Cre-Kdm2a, Kdm2a) promoted macrophage M2...
10.
Zhang J, Chen L, Wang F, Zou Y, Li J, Luo J, et al.
Diabetologia
. 2020 Feb;
63(5):987-1001.
PMID: 32072192
Aims/hypothesis: High-mobility group box 1 (HMGB1), an evolutionarily conserved chromosomal protein, was rediscovered to be a 'danger signal' (alarmin) that alerts the immune system once released extracellularly. Therefore, it has...