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Loes Verheyden

Explore the profile of Loes Verheyden including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 88
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Recent Articles
1.
Vanderschaeghe H, Houlleberghs M, Verheyden L, Dom D, Chandran C, Radhakrishnan S, et al.
Anal Chem . 2022 Dec; PMID: 36579853
Porous silica is used as a drug delivery agent to improve the bioavailability of sparsely soluble compounds. In this approach, the active pharmaceutical ingredient (API) is commonly loaded into the...
2.
Houlleberghs M, Verheyden L, Voorspoels F, Chandran C, Duerinckx K, Radhakrishnan S, et al.
RSC Adv . 2022 Apr; 12(13):7830-7834. PMID: 35424734
Mixing dry carbomer powder with water using magneto-hydrodynamic mixing yielded carbomer dispersions with higher viscosity and increased storage modulus as compared to conventional high shear mixing. H NMR spectroscopy demonstrated...
3.
Radhakrishnan S, Colaux H, Chandran C, Dom D, Verheyden L, Taulelle F, et al.
Anal Chem . 2020 Aug; 92(19):13004-13009. PMID: 32830954
A protocol for the detection of trace amounts of quartz in amorphous silica gels by NMR spectroscopy was developed and tested on commercially available samples. Using natural abundance Si MAS...
4.
Bukara K, Schueller L, Rosier J, Martens M, Daems T, Verheyden L, et al.
Eur J Pharm Biopharm . 2016 Sep; 108:220-225. PMID: 27648957
Formulating poorly water soluble drugs using ordered mesoporous silica materials is an emerging approach to tackle solubility-related bioavailability problems. The current study was conducted to assess the bioavailability-enhancing potential of...
5.
Bukara K, Schueller L, Rosier J, Daems T, Verheyden L, Eelen S, et al.
J Pharm Sci . 2016 Jul; 105(8):2381-5. PMID: 27364460
The present study aims to evaluate the in vitro and in vivo performance of ordered mesoporous silica (OMS) as a carrier for the poorly water-soluble compound fenofibrate. Fenofibrate was loaded...
6.
Kiekens F, Eelen S, Verheyden L, Daems T, Martens J, Van den Mooter G
J Pharm Sci . 2011 Dec; 101(3):1136-44. PMID: 22190350
The aim of this study was to investigate the bioavailability enhancement of the biopharmaceutics classification system class II compound ezetimibe loaded in ordered mesoporous silica (OMS) in dogs. The OMS...
7.
Dillen K, Vandervoort J, Van den Mooter G, Verheyden L, Ludwig A
Int J Pharm . 2004 Apr; 275(1-2):171-87. PMID: 15081148
Poly(lactide-co-glycolide) nanoparticles incorporating ciprofloxacin HCl were prepared by means of a W/O/W emulsification solvent evaporation method. The stabiliser selected was poly(vinylalcohol). A 2(4) full factorial design based on four independent...