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Lode De Cauwer

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Articles 15
Citations 283
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Recent Articles
11.
Ratman D, Mylka V, Bougarne N, Pawlak M, Caron S, Hennuyer N, et al.
Nucleic Acids Res . 2016 Sep; 44(22):10539-10553. PMID: 27576532
Adaptation to fasting involves both Glucocorticoid Receptor (GRα) and Peroxisome Proliferator-Activated Receptor α (PPARα) activation. Given both receptors can physically interact we investigated the possibility of a genome-wide cross-talk between...
12.
Thoonen R, Cauwels A, Decaluwe K, Geschka S, Tainsh R, Delanghe J, et al.
Nat Commun . 2015 Oct; 6:8482. PMID: 26442659
Oxidative stress, a central mediator of cardiovascular disease, results in loss of the prosthetic haem group of soluble guanylate cyclase (sGC), preventing its activation by nitric oxide (NO). Here we...
13.
Icardi L, Mori R, Gesellchen V, Eyckerman S, De Cauwer L, Verhelst J, et al.
Proc Natl Acad Sci U S A . 2012 Jul; 109(30):12058-63. PMID: 22783022
Tyrosine phosphorylation is a hallmark for activation of STAT proteins, but their transcriptional activity also depends on other secondary modifications. Type I IFNs can activate both the ISGF3 (STAT1:STAT2:IRF9) complex...
14.
Reber L, Daubeuf F, Plantinga M, De Cauwer L, Gerlo S, Waelput W, et al.
J Immunol . 2012 Mar; 188(7):3478-87. PMID: 22393156
The glucocorticoid receptor (GR) is a transcription factor able to support either target gene activation via direct binding to DNA or gene repression via interfering with the activity of various...
15.
Icardi L, Lievens S, Mori R, Piessevaux J, De Cauwer L, De Bosscher K, et al.
FASEB J . 2011 Sep; 26(1):240-9. PMID: 21957129
The antiviral and antiproliferative responses mediated by type I interferons (IFNs) depend on JAK/STAT signaling and ISGF3 (STAT1:STAT2:IRF9)-dependent transcription. In addition, type I IFNs stimulate STAT3 activation in many cell...