Lixiang Zhai
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Explore the profile of Lixiang Zhai including associated specialties, affiliations and a list of published articles.
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25
Citations
341
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Recent Articles
1.
Zhuang M, Zhai L, Zhang H, Chen Q, Xiong R, Liu Y, et al.
Front Public Health
. 2024 Dec;
12:1450744.
PMID: 39697290
Background: In the field of public health, the prevention and management of infectious diseases in rural regions have always been crucial. This study aims to analyze the factors influencing rural...
2.
Chen J, Xu J, Wu Z, Meng X, Yu Y, Ginoux P, et al.
Sci Adv
. 2024 Sep;
10(37):eado0885.
PMID: 39270018
Ice-nucleating particles (INPs) can initiate cloud ice formation, influencing cloud radiative effects (CRE) and climate. However, the knowledge of INP sources, concentrations, and their impact on CRE over the Tibetan...
3.
Cheng K, Shi J, Huang C, Tan H, Ning Z, Lyu C, et al.
Comput Biol Med
. 2024 Jun;
178:108775.
PMID: 38941901
Background: CDD-2103 is an herbal prescription used to treat ulcerative colitis (UC). This study aimed to uncover its mechanism by integrating metabolomics and serum-feces pharmacochemistry-based network pharmacology. Methods: A DSS-induced...
4.
Guo X, Asthana P, Zhai L, Cheng K, Gurung S, Huang J, et al.
Nat Commun
. 2024 Feb;
15(1):1034.
PMID: 38310105
Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an ongoing need to identify safe and tolerable...
5.
Zhai L, Xiao H, Lin C, Wong H, Lam Y, Gong M, et al.
Nat Commun
. 2023 Aug;
14(1):4986.
PMID: 37591886
The incidence of metabolic syndrome is significantly higher in patients with irritable bowel syndrome (IBS), but the mechanisms involved remain unclear. Gut microbiota is causatively linked with the development of...
6.
Du L, Zhang Z, Zhai L, Xu S, Yang W, Huang C, et al.
Chin Med
. 2023 Jul;
18(1):87.
PMID: 37468912
Background: Dysregulation of gut microbiota-host bile acid (BA) co-metabolism is a critical pathogenic factor of diarrhea-predominant irritable bowel syndrome (IBS-D). Traditional Chinese Medicine (TCM), instructed by pattern differentiation, is effective...
7.
Wu P, Chang C, Zhu G, Zhai L, Zhang X, Huan Q, et al.
Drug Des Devel Ther
. 2023 May;
17:1531-1546.
PMID: 37249930
Purpose: To explore the potential mechanism of glycosidic fraction of (GPS) extract for the treatment of colitis using UPLC-QTOF-MS analysis, network pharmacology and experimental research. Methods: The active components of...
8.
Yu L, Huang C, Yang W, Ren Z, Li L, Cheng H, et al.
Front Pharmacol
. 2023 Jan;
13:1010484.
PMID: 36699075
Cinnamon protects against irritable bowel syndrome with diarrhea (IBS-D) in humans, but its efficacy and underlying mechanism of action remain poorly understood. Maternally separated (MS) IBS-D rat model and 2,4,6-trinitrobenzene...
9.
Zhai L, Huang C, Ning Z, Zhang Y, Zhuang M, Yang W, et al.
Cell Host Microbe
. 2022 Dec;
31(1):33-44.e5.
PMID: 36495868
Diarrhea-predominant irritable bowel syndrome (IBS-D), a globally prevalent functional gastrointestinal (GI) disorder, is associated with elevated serotonin that increases gut motility. While anecdotal evidence suggests that the gut microbiota contributes...
10.
Zhang X, Xu J, Zhai L, Zhao W
Environ Sci Technol
. 2022 Oct;
56(20):14296-14305.
PMID: 36198091
The Tibet Autonomous Region in China is a unique place with high altitude and special Tibetan culture. The residents have different living habits and domestic fuels from those in other...