Liu-Yi Liu
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Explore the profile of Liu-Yi Liu including associated specialties, affiliations and a list of published articles.
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25
Citations
210
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Recent Articles
1.
Li Y, Liu B, Zheng Y, Hu M, Liu L, Li C, et al.
J Med Chem
. 2024 Sep;
67(18):16235-16247.
PMID: 39250558
Triggering ferroptosis represents a promising anticancer therapeutic strategy, but the development of a selective ferroptosis inducer for cancer-specific therapy remains a great challenge. Herein, a HS-responsive iridium(III) complex has been...
2.
Zeng Y, Liu L, Ma T, Liu Y, Liu B, Liu W, et al.
Angew Chem Int Ed Engl
. 2024 Aug;
63(49):e202410803.
PMID: 39180126
The integration of pyroptosis and ferroptosis hybrid cell death induction to augment immune activation represents a promising avenue for anti-tumor treatment, but there is a lack of research. Herein, we...
3.
Liu W, Zhu B, Liu L, Xia X, Jang J, Dickerhoff J, et al.
Nucleic Acids Res
. 2024 Jul;
52(16):9397-9406.
PMID: 39077944
G-quadruplex (G4) structures play integral roles in modulating biological functions and can be regulated by small molecules. The MYC gene is critical during tumor initiation and malignant progression, in which...
4.
Ma T, Liu L, Zeng Y, Ding K, Zhang H, Liu W, et al.
Chem Sci
. 2024 Jun;
15(25):9756-9774.
PMID: 38939132
G-quadruplexes (G4s) are atypical nucleic acid structures involved in basic human biological processes and are regulated by small molecules. To date, pyridostatin and its derivatives [, PyPDS (4-(2-aminoethoxy)- , -bis(4-(2-(pyrrolidin-1-yl)...
5.
Chen Q, Liu L, Tian Z, Fang Z, Wang K, Shao X, et al.
Cell Rep
. 2023 Nov;
42(12):113472.
PMID: 37999975
Mitochondria are dynamic organelles that undergo fusion and fission events, in which the mitochondrial membrane and DNA (mtDNA) play critical roles. The spatiotemporal organization of mtDNA reflects and impacts mitochondrial...
6.
Rao L, Hao L, Liu L, Zeng Y, Liang B, Liu W, et al.
Chem Commun (Camb)
. 2023 Oct;
59(89):13348-13351.
PMID: 37872783
A TTPP probe was developed to distinguish G-quadruplexes (G4s) from other nucleic acid topologies through longer fluorescence lifetimes and higher quantum yields. In fluorescence lifetime imaging microscopy, TTPP enabled the...
7.
Liu L, Ma T, Zeng Y, Liu W, Zhang H, Mao Z
Angew Chem Int Ed Engl
. 2023 Jul;
62(36):e202305645.
PMID: 37464955
G-quadruplexes (G4s) have been revived as promising therapeutic targets with the development of immunotherapy, but the G4-mediated immune response remains unclear. We designed a novel class of G4-binding organic-platinum hybrids,...
8.
Ling Y, Xia X, Hao L, Wang W, Zhang H, Liu L, et al.
Angew Chem Int Ed Engl
. 2022 Aug;
61(43):e202210988.
PMID: 35979672
Activation of the cyclic GMP-AMP synthase-stimulator of the interferon gene (cGAS-STING) pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis is a feasible way to stimulate the...
9.
Zhu B, He J, Xia X, Jiang J, Liu W, Liu L, et al.
Chem Sci
. 2022 Aug;
13(28):8371-8379.
PMID: 35919711
Thrombin Binding Aptamer (TBA) is a monomolecular well-defined two G-tetrad antiparallel G-quadruplex DNA that inhibits the activity of human α-thrombin. In this report, we synthesized a quasi-cross-shaped platinum(ii) compound (L'LPt)...
10.
Liu W, Zhu B, Liu L, Xia X, Mao Z
Nucleic Acids Res
. 2022 Jun;
50(14):7816-7828.
PMID: 35766415
G-quadruplex (G4) transitions play integral roles in regulating biological functions and can be modified by ligands. However, little is known about G4 transitions. Herein, we reveal distinct pathways of a...