Litong Nie
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Explore the profile of Litong Nie including associated specialties, affiliations and a list of published articles.
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30
Citations
1093
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Recent Articles
1.
Huang M, Yang C, Nie L, Zhang H, Zhu D, Wang C, et al.
Nucleic Acids Res
. 2025 Jan;
53(1).
PMID: 39778868
Cell cycle checkpoints are the regulatory mechanisms that secure the strict order of cellular events for cell division that ensure genome integrity. It has been proposed that mitosis initiation depends...
2.
Feng X, Yang C, Huang Y, Su D, Wang C, Wilson L, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(39):e2406325121.
PMID: 39298484
Immune evasion is not only critical for tumor initiation and progression, but also determines the efficacy of immunotherapies. Through iterative in vivo CRISPR screens with seven syngeneic tumor models, we...
3.
Li S, Tang M, Xiong Y, Feng X, Wang C, Nie L, et al.
Oncogene
. 2024 Jul;
43(35):2621-2634.
PMID: 39068216
BRCA1, a breast cancer susceptibility gene, has emerged as a central mediator that brings together multiple signaling complexes in response to DNA damage. The A, B, and C complexes of...
4.
Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, et al.
Elife
. 2024 Apr;
12.
PMID: 38578205
Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response. PARG, the most active dePARylation...
5.
Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, et al.
Protein Cell
. 2024 Mar;
15(9):686-703.
PMID: 38430542
Ferroptosis has been recognized as a unique cell death modality driven by excessive lipid peroxidation and unbalanced cellular metabolism. In this study, we established a protein interaction landscape for ferroptosis...
6.
Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, et al.
bioRxiv
. 2023 Aug;
PMID: 37577639
Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response. PARG, the most active dePARylation...
7.
Huang M, Yao F, Nie L, Wang C, Su D, Zhang H, et al.
Mol Cell
. 2023 Aug;
83(15):2810-2828.e6.
PMID: 37541219
DNA damage-activated signaling pathways are critical for coordinating multiple cellular processes, which must be tightly regulated to maintain genome stability. To provide a comprehensive and unbiased perspective of DNA damage...
8.
Park J, Zhang H, Nie L, Wang C, Huang M, Feng X, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047518
Etoposide (ETO) is an anticancer drug that targets topoisomerase II (TOP2). It stabilizes a normally transient TOP2-DNA covalent complex (TOP2cc), thus leading to DNA double-strand breaks (DSBs). Tyrosyl-DNA phosphodiesterases two...
9.
Liu X, Nie L, Zhang Y, Yan Y, Wang C, Colic M, et al.
Nat Cell Biol
. 2023 Feb;
25(3):404-414.
PMID: 36747082
SLC7A11-mediated cystine uptake suppresses ferroptosis yet promotes cell death under glucose starvation; the nature of the latter cell death remains unknown. Here we show that aberrant accumulation of intracellular disulfides...
10.
Zhang S, Lee S, Nie L, Huang Y, Zou G, Jung Y, et al.
Cancer Commun (Lond)
. 2022 Nov;
43(1):159-163.
PMID: 36336962
No abstract available.