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Lishan Fang

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Articles 23
Citations 977
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Recent Articles
1.
Fang L, Li J, Lin W, Zeng L, Yu L, Chen Z, et al.
ChemistryOpen . 2024 Jun; 13(10):e202400107. PMID: 38837681
Oxidative stress caused by pregnancy-induced hypertension syndrome significantly affects the health of pregnant women. Hydrogen sulfide is a typical gaseous signal molecule against oxidative stress, and it is of profound...
2.
Gong H, Chen S, Liu S, Hu Q, Li Y, Li Y, et al.
Cell Mol Life Sci . 2024 Jan; 81(1):39. PMID: 38214751
Colorectal cancer (CRC) is characterized by a complex tumor inflammatory microenvironment, while angiogenesis and immunosuppression frequently occur concomitantly. However, the exact mechanism that controls angiogenesis and immunosuppression in CRC microenvironment...
3.
Liu S, Hu Q, Xie Z, Chen S, Li Y, Quan N, et al.
J Cancer Res Clin Oncol . 2023 Aug; 149(17):15589-15608. PMID: 37653101
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors. Endoplasmic reticulum stress (ERS) plays an essential role in PDAC progression. Here, we aim to identify the ERS-related...
4.
Bai X, Yao Q, Li G, Guan G, Fan Y, Cao X, et al.
J Microbiol Biotechnol . 2023 Aug; 33(10):1299-1308. PMID: 37528558
is an important economic nut tree that is endemic to eastern China. As such, outbreaks of root rot disease in result in reduced yields and serious economic losses. Moreover, while...
5.
Fang L, Chen S, Gong H, Xia S, Guan S, Quan N, et al.
Front Oncol . 2023 Feb; 12:1060508. PMID: 36727081
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive lethal malignancy. An effective prognosis prediction model is urgently needed for treatment optimization. Methods: The differentially expressed unfolded protein response (UPR)‒related...
6.
Fang L, Ford-Roshon D, Russo M, OBrien C, Xiong X, Gurjao C, et al.
Nat Commun . 2022 Jun; 13(1):3181. PMID: 35676246
The RNF43_p.G659fs mutation occurs frequently in colorectal cancer, but its function remains poorly understood and there are no specific therapies directed against this alteration. In this study, we find that...
7.
Jiang L, Lin C, Song L, Wu J, Chen B, Ying Z, et al.
J Clin Invest . 2021 Nov; 131(22). PMID: 34779411
No abstract available.
8.
Thornton A, Fang L, Lo A, McSharry M, Haan D, OBrien C, et al.
PLoS Comput Biol . 2021 Jul; 17(7):e1009132. PMID: 34214079
While advancements in genome sequencing have identified millions of somatic mutations in cancer, their functional impact is poorly understood. We previously developed the expression-based variant impact phenotyping (eVIP) method to...
9.
Jian Y, Huang X, Fang L, Wang M, Liu Q, Xu H, et al.
J Exp Clin Cancer Res . 2021 Feb; 40(1):56. PMID: 33541412
Background: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high proliferative activity. TNBC tumors exhibit elevated MYC expression and altered expression of MYC regulatory genes,...
10.
Fang L, Wu S, Zhu X, Cai J, Wu J, He Z, et al.
Oncogene . 2018 Sep; 38(6):896-912. PMID: 30181549
Non-small cell lung cancer (NSCLC) remains a major cause of death worldwide. As metastatic disease is primarily responsible for the poor clinical outcome of NSCLC, it is important to understand...